BENZAMIDINE DERIVATIVES

Title:

BENZAMIDINE DERIVATIVES

Document Type and Number:

WIPO Patent Application WO/1998/031661

Kind Code:

A1

Abstract:

Benzamidine derivatives involving compounds represented by formulae (a) and (b) and analogs thereof or pharmaceutically acceptable salts thereof. These compounds show anticoagulant effects based on their excellent effects of inhibiting activated blood coagulation factor X, which makes them useful as an anticoagulant.

Inventors:

TAKAYANAGI MASARU (JP)
SAGI KAZUYUKI (JP)
NAKAGAWA TADAKIYO (JP)
YAMANASHI MASAHIRO (JP)
KAYAHARA TAKASHI (JP)
TAKEHANA SHUNJI (JP)
FUKUDA YUMIKO (JP)
TAKAHASHI MITSUO (JP)
SHOJI MASATAKA (JP)

Application Number:

PCT/JP1998/000176

Publication Date:

July 23, 1998

Filing Date:

January 19, 1998

Export Citation:

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Assignee:

AJINOMOTO KK (JP)
TAKAYANAGI MASARU (JP)
SAGI KAZUYUKI (JP)
NAKAGAWA TADAKIYO (JP)
YAMANASHI MASAHIRO (JP)
KAYAHARA TAKASHI (JP)
TAKEHANA SHUNJI (JP)
FUKUDA YUMIKO (JP)
TAKAHASHI MITSUO (JP)
SHOJI MASATAKA (JP)

International Classes:

C07C257/18; C07C279/18; C07C311/13; C07C311/19; C07C327/48; C07D207/327; C07D209/08; C07D209/16; C07D211/34; C07D211/46; C07D211/62; C07D211/70; C07D213/56; C07D213/74; C07D233/26; C07D233/54; C07D239/06; C07D295/155; C07D295/192; C07D295/215; C07D453/02; C07F9/59; C07D207/32; (IPC1-7): C07C257/18; C07C271/22; C07C279/18; C07C309/64; C07C311/06; C07C311/14; C07C311/15; C07C323/62; C07D207/325; C07D213/26; C07D233/26; C07D239/06; C07D307/46; C07D211/62; C07D211/92; C07D211/34; C07D295/16; C07D209/08; C07D209/14; C07D207/12; C07D401/04; C07D207/08; C07D453/02; A61K31/34; A61K31/44; A61K31/40; A61K31/415; A61K31/505; A61K31/215; A61K31/195; A61K31/445

Domestic Patent References:

WO1997024118A1	1997-07-10
WO1996022288A1	1996-07-25

Foreign References:

EP0672658A1	1995-09-20
JPH07330695A	1995-12-19
JPH07391T

Other References: