Title:
BENZAZEPINE DERIVATIVE, CONJUGATE CONTAINING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/067841
Kind Code:
A1
Abstract:
Provided are a benzazepine derivative, a conjugate containing same, and use thereof. Provided is an antibody-immunostimulatory conjugate represented by formula (I) or a pharmaceutically acceptable salt thereof. The benzazepine derivative has a good regulation effect on TLR8, and can effectively treat, relieve and/or prevent various related diseases, such as cancer, caused by immunosuppression.
Inventors:
ZHANG WEI (CN)
QIN PING (CN)
YANG WEI (CN)
WANG LONGSHENG (CN)
GAO DAXIN (CN)
QIN PING (CN)
YANG WEI (CN)
WANG LONGSHENG (CN)
GAO DAXIN (CN)
Application Number:
PCT/CN2023/122797
Publication Date:
April 04, 2024
Filing Date:
September 28, 2023
Export Citation:
Assignee:
SHANGHAI DE NOVO PHARMATECH CO LTD (CN)
International Classes:
C07D223/16; A61K47/68; A61P35/00; C07K16/28
Domestic Patent References:
| WO2020056008A1 | 2020-03-19 | |||
| WO2020056194A1 | 2020-03-19 |
Foreign References:
| CN115448917A | 2022-12-09 | |||
| CN110612104A | 2019-12-24 | |||
| CN114746404A | 2022-07-12 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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