BENZENE DERIVATIVES AND USE THEREOF AS DRUGS

WIPO Patent Application WO/2001/035955

A1

Benzene derivatives represented by general formula (I) or pharmacologically acceptable salts thereof; and drugs, particularly antihypocytotic agents, containing the derivatives or the salts as the active ingredient. The derivatives can induce the production of blood platelets, white blood cells, red blood cells, and so on, and are useful in chemotherapy of cancers, radiotherapy or drug therapy and effective in the prevention or treatment of hypocytosis due to immune disorder, anemia or the like.

KANEEDA MASANOBU (JP)
SUGAWARA YUJI (JP)
KAWAI HIDEKI (JP)
OKANO KIYOSHI (JP)
ADACHI YASUMOTO (JP)

PCT/JP2000/008058

May 25, 2001

November 16, 2000

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TORAY INDUSTRIES (JP)
KANEEDA MASANOBU (JP)
SUGAWARA YUJI (JP)
KAWAI HIDEKI (JP)
OKANO KIYOSHI (JP)
ADACHI YASUMOTO (JP)

A61K31/12; A61K31/165; A61K31/167; A61K31/18; A61K31/192; A61K31/216; A61K31/235; A61K31/255; A61K31/277; A61K31/37; A61K31/381; A61K31/41; A61P7/06; A61P43/00; C07C49/83; C07C49/84; C07C59/90; C07C205/45; C07C205/56; C07C205/61; C07C235/78; C07C255/56; C07C255/57; C07C311/09; C07C317/24; C07D333/22; C07F9/38; (IPC1-7): A61K31/12; A61K31/167; A61K31/18; A61K31/192; A61K31/216; A61K31/235; A61K31/275; A61K31/37; A61K31/381; A61K31/41; A61K31/661; A61K31/662; A61P7/06; A61P43/00; C07C49/83; C07C49/84; C07C59/90; C07C205/45; C07C205/56; C07C205/61; C07C235/64; C07C235/78; C07C255/56; C07C255/57; C07C311/08; C07C317/24; C07C317/46; C07D257/04; C07D333/22; C07F9/38

WO1999016763A1	1999-04-08
WO1998003505A2	1998-01-29

JPH0543518A	1993-02-23
DE2909754A1	1980-09-18
US3816538A	1974-06-11
GB1282703A	1972-07-26
JPH10212271A	1998-08-11
JPH08143571A	1996-06-04
US5098918A	1992-03-24

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