Title:
BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME
Document Type and Number:
WIPO Patent Application WO2001000588
Kind Code:
A8
Abstract:
Benzimidazole compounds of general formula (I) or salts thereof, which exhibit inhibitory activities against the conversion of macrophages into foam cells and are useful as the active ingredient of drugs to be used in the prevention and/or treatment of arteriosclerosis wherein R<1> is hydrogen, halogeno, lower alkyl, or lower alkoxy; R<2> is hydrogen, alkyl, or acyl; R<3> is a substituent on the ring; A is O or CH2, or alternatively A represents a CH group binding to an adjacent carbon atom through a double bond; L is C4-C8 alkylene or an ethylene-oxy connecting group represented by the general formula: (CH2CH2O)nCH2CH2 (wherein n is 1 or 2); X is O, S, or methylene; and m is 0 or 1.
Inventors:
AOKI KOZO (JP)
AIKAWA KAZUHIRO (JP)
KAWAKAMI MASAYUKI (JP)
YAN YONGZHE (JP)
AIKAWA KAZUHIRO (JP)
KAWAKAMI MASAYUKI (JP)
YAN YONGZHE (JP)
Application Number:
PCT/JP2000/004203
Publication Date:
March 08, 2001
Filing Date:
June 27, 2000
Export Citation:
Assignee:
FUJI PHOTO FILM CO LTD (JP)
AOKI KOZO (JP)
AIKAWA KAZUHIRO (JP)
KAWAKAMI MASAYUKI (JP)
YAN YONGZHE (JP)
AOKI KOZO (JP)
AIKAWA KAZUHIRO (JP)
KAWAKAMI MASAYUKI (JP)
YAN YONGZHE (JP)
International Classes:
A61P3/06; A61P9/10; C07D401/12; (IPC1-7): C07D235/28; C07D401/12; C07D401/14; C07D413/12; C07D495/04; C07D235/26; A61K31/454; A61K31/5377; A61K31/4709; A61K31/4725; A61K31/538; A61K31/4365; A61P9/10; A61P3/06
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