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Patent Searching and Data


Title:
BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME
Document Type and Number:
WIPO Patent Application WO/2018/008989
Kind Code:
A1
Abstract:
The present invention provides a benzo[d]thiazole derivative or a pharmaceutically acceptable salt thereof, a method for producing the same, and a pharmaceutical composition including the same. The benzo[d]thiazole derivative or the pharmaceutically acceptable salt thereof selectively inhibits a protein-protein interaction of KRS and laminin receptor (LR), thereby being able to inhibit the movement of cancer cells. Accordingly, the benzo[d]thiazole derivative or the pharmaceutically acceptable salt thereof can be usefully applied to the prevention or treatment of cancer cell metastasis-mediated diseases.

Inventors:
OH SE-WOONG (KR)
HUR YOUN (KR)
PARK JIN-HWI (KR)
JOO JAE-EUN (KR)
KANG HO-WOONG (KR)
CHO HYOK-JUN (KR)
LEE EUI-CHUL (KR)
PARK CHAN-SUN (KR)
KIM DONG-HYUN (KR)
KIM JONG-GYUN (KR)
NAM SU-YOUN (KR)
Application Number:
PCT/KR2017/007201
Publication Date:
January 11, 2018
Filing Date:
July 06, 2017
Export Citation:
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Assignee:
YUHAN CORP (KR)
International Classes:
C07D277/82; A61K9/00; A61K9/08; A61K9/20; A61K31/428
Domestic Patent References:
WO2009126635A12009-10-15
WO2003074495A12003-09-12
WO2013043001A12013-03-28
WO2006094235A12006-09-08
Other References:
COMESS, K. M. ET AL.: "Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases", ACS CHEM. BIOL., vol. 6, 2011, pages 234 - 244, XP055451025
See also references of EP 3483149A4
Attorney, Agent or Firm:
OH, Kook-Jin (KR)
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