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Patent Searching and Data


Title:
BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS
Document Type and Number:
WIPO Patent Application WO2005009104
Kind Code:
A3
Abstract:
The present invention is directed to hepatocyte nuclear factor 4a (HNF-4a) receptor modulator compounds. This invention is also directed to pharmaceutical compositions containing such compounds as well as methods of using such compounds and pharmaceutical compositions for modulating HNF-4a receptors as well as processes mediated by HNF-4a receptors. Also provided are methods of making such compounds and pharmaceutical compositions, as well as intermediates used in their synthesis.

Inventors:
MAPES CHRISTOPHER (US)
KARANEWSKY DONALD (US)
THOMPSON ANTHONY (US)
MICHELLYS PIERRRE (US)
RUPPAR DANIEL (US)
CHEN JYUN-HUNG (US)
Application Number:
US2004023788W
Publication Date:
December 29, 2005
Filing Date:
July 16, 2004
Export Citation:
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Assignee:
LIGAND PHARMACUETICALS INCORPORATED
MAPES, CHRISTOPHER
KARANEWSKY, DONALD
THOMPSON, ANTHONY
MICHELLYS, PIERRRE
RUPPAR, DANIEL
CHEN, JYUN-HUNG
International Classes:
C07C51/16; C07C59/68; C07C59/90; C07C61/00; C07C69/618; C07C69/712; C07C69/734; C07C69/736; C07C69/76; C07C69/92; C07C229/34; C07C229/38; C07C229/42; C07C233/81; C07C323/62; C07D213/30; C07D319/18; C07D333/16; (IPC1-7): C07C69/76; C07C61/00; C07C51/16
Other References:
DATABASE CAPLUS [online] 27 June 2002 (2002-06-27), BESWICK ET AL: "Thia-and oxazoles and their use as hPPAR delta agonists", XP002994319, Database accession no. (2002:487541)
DATABASE CAPLUS [online] 19 December 2002 (2002-12-19), BROOKS ET AL: "Preparation of substituted 3-phenyl1-2alkoxypropanic acids and analogs as modulators or peroxisome profilerator activated receptors for treatment of daibetes and related conditions", XP002994320, Database accession no. (2002:964313)
DATABASE CAPLUS [online] 11 March 1999 (1999-03-11), TAJIMA ET AL: "Preparation of phenylalkanoic acid derivatives as peroxisome profilerator-activated receptor controllers", XP002994321, Database accession no. (1999:184126)
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