Title:
BENZOIMIDAZOLE DERIVATIVES AS ANTICANCER AGENTS
Document Type and Number:
WIPO Patent Application WO/2018/054989
Kind Code:
A9
Abstract:
The invention relates to benzoimidazole derivatives, acting as anticancer drugs, as well as pharmaceutical composition containing said compounds. These compounds are able to firstly inhibit the protein/protein interactions of the MAP Kinase Erk, leading to inhibition of proliferation and secondly to induce apoptosis in human cancer cell lines.
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| JP2008516939 | Chemical compound |
| WO/2002/092578 | QUINAZOLINE DERIVATIVES |
Inventors:
RENNO TOUFIC (FR)
COSTE-INVERNIZZI ISABELLE (FR)
GIRAUD STÉPHANE (FR)
LEBECQUE SERGE (FR)
COSTE-INVERNIZZI ISABELLE (FR)
GIRAUD STÉPHANE (FR)
LEBECQUE SERGE (FR)
Application Number:
PCT/EP2017/073801
Publication Date:
July 05, 2018
Filing Date:
September 20, 2017
Export Citation:
Assignee:
CENTRE LEON BERARD (FR)
HOSPICES CIVILS LYON (FR)
UNIV CLAUDE BERNARD LYON (FR)
CENTRE NAT RECH SCIENT (FR)
INST NAT SANTE RECH MED (FR)
HOSPICES CIVILS LYON (FR)
UNIV CLAUDE BERNARD LYON (FR)
CENTRE NAT RECH SCIENT (FR)
INST NAT SANTE RECH MED (FR)
International Classes:
C07D403/12; A61K31/4184; A61P35/00; C07D235/18; C07D401/04; C07D401/12; C07D401/14; C07D403/04; C07D407/12; C07D407/14; C07D413/12; C07D417/12; C07D487/04
Attorney, Agent or Firm:
REGIMBEAU (FR)
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