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Title:
BENZOLACTAM DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/1995/009160
Kind Code:
A1
Abstract:
A benzolactam derivative represented by general formula (I) and an antiretroviral drug containing the same as the active ingredient, wherein n represents an integer of 1 to 3; R1 represents linear or branched alkyl, or aralkyl; R2 represents linear or branched alkyl; and R3 and R4 represent each independently hydrogen or linear or branched alkyl, provided when R3 and R4 are bonded respectively to the adjacent carbon atoms of the benzene ring, they may be combined together with the ring carbon atoms to form a cycloalkane ring which may be substituted.

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Inventors:
SHUDO KOICHI (JP)
ENDO YASUYUKI (JP)
FUJIWARA TAMIO (JP)
SATO AKIHIKO (JP)
Application Number:
PCT/JP1994/001561
Publication Date:
April 06, 1995
Filing Date:
September 22, 1994
Export Citation:
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Assignee:
SHIONOGI & CO (JP)
SHUDO KOICHI (JP)
ENDO YASUYUKI (JP)
FUJIWARA TAMIO (JP)
SATO AKIHIKO (JP)
International Classes:
C07D245/06; (IPC1-7): C07D245/06; A61K31/395
Foreign References:
JPH04275287A1992-09-30
Other References:
J. AM. CHEM. SOC., Vol. 115, No. 10, (1993), A.P. KOZIKOWSKI et al., "Synthesis, Molecular Modeling, 2-DNMR, and Biological Evaluation of ILV Mimic as Potential Modulators of Protein Kinase C", p. 3957-3965.
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