Title:
BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS
Document Type and Number:
WIPO Patent Application WO/2019/070093
Kind Code:
A1
Abstract:
The present disclosure provides a compound of general Formula (I) having c-abl kinase inhibitory activity or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound, and a method useful to treat or prevent neurodegenerative diseases using the compound.
Inventors:
LEE JINHWA (KR)
JO SUYEON (KR)
PARK A YEONG (KR)
LEE GWIBIN (KR)
KIM JAE EUN (KR)
KIM MISOON (KR)
JUNG GYOOSEUNG (KR)
LIM SEUNG MOOK (KR)
LIM KEONSEUNG (KR)
LEE MINWOO (KR)
YANG HEEKYOUNG (KR)
KIM HYONAM (KR)
KIM HYEONGJUN (KR)
LI WANJUN (CN)
FAN MINGZHU (CN)
JO SUYEON (KR)
PARK A YEONG (KR)
LEE GWIBIN (KR)
KIM JAE EUN (KR)
KIM MISOON (KR)
JUNG GYOOSEUNG (KR)
LIM SEUNG MOOK (KR)
LIM KEONSEUNG (KR)
LEE MINWOO (KR)
YANG HEEKYOUNG (KR)
KIM HYONAM (KR)
KIM HYEONGJUN (KR)
LI WANJUN (CN)
FAN MINGZHU (CN)
Application Number:
PCT/KR2018/011660
Publication Date:
April 11, 2019
Filing Date:
October 01, 2018
Export Citation:
Assignee:
1ST BIOTHERAPEUTICS INC (KR)
International Classes:
C07D277/82; C07D417/04; C07D417/10; C07D513/04
Domestic Patent References:
| WO2007095588A1 | 2007-08-23 | |||
| WO2010100144A1 | 2010-09-10 | |||
| WO2001057008A1 | 2001-08-09 | |||
| WO2010008847A2 | 2010-01-21 | |||
| WO2010144909A1 | 2010-12-16 |
Foreign References:
| US8993580B2 | 2015-03-31 | |||
| US20110172228A1 | 2011-07-14 | |||
| US201762566649P | 2017-10-02 | |||
| US201862666800P | 2018-05-04 | |||
| US201862696432P | 2018-07-11 | |||
| KR20140107153A | 2014-09-04 |
Other References:
NAT REV MOL CELL BIOL, vol. 5, 2004, pages 33 - 44
HUMAN MOLECULAR GENETICS, vol. 23, no. 11, 2014
THE JOURNAL OF NEUROSCIENCE, vol. 31, no. 1, 2011, pages 157 - 163
IMAMURA ET AL., SCI. TRANSL. MED., vol. 9, 2017
J NEURAL TRANSM VIENNA AUSTRIA, vol. 2016, 1996, pages 123
HUM MOL GENET., 15 August 2013 (2013-08-15)
See also references of EP 3692023A4
HUMAN MOLECULAR GENETICS, vol. 23, no. 11, 2014
THE JOURNAL OF NEUROSCIENCE, vol. 31, no. 1, 2011, pages 157 - 163
IMAMURA ET AL., SCI. TRANSL. MED., vol. 9, 2017
J NEURAL TRANSM VIENNA AUSTRIA, vol. 2016, 1996, pages 123
HUM MOL GENET., 15 August 2013 (2013-08-15)
See also references of EP 3692023A4
Attorney, Agent or Firm:
PHIL & ONZI INT'L PATENT & LAW FIRM (KR)
Download PDF: