Title:
BENZOXAZINE ALPHA-1 ADRENERGIC COMPOUNDS
Document Type and Number:
WIPO Patent Application WO2002020533
Kind Code:
A3
Abstract:
The present invention relates to compounds having formula I and to pharmaceutically acceptable salts thereof. Compounds of formula I inhibit a1 adrenoreceptors and may be useful for treating benign prostatic hyperplasia (also called benign prostatic hypertrophy) and other urological diseases such as bladder outlet obstruction, neurogenic bladder and gynecological syndromes.
Inventors:
BASHA FATIMA Z
WENDT MICHAEL D
PRATT JOHN K
WENDT MICHAEL D
PRATT JOHN K
Application Number:
PCT/US2001/026878
Publication Date:
August 22, 2002
Filing Date:
August 29, 2001
Export Citation:
Assignee:
ABBOTT LAB (US)
International Classes:
A61P13/00; C07D519/00; (IPC1-7): C07D519/00; A61K31/5365; A61P13/00
Domestic Patent References:
| WO1998037893A1 | 1998-09-03 |
Other References:
BAXTER E W ET AL: "Hindered rotation congeners of mazapertine: high affinity ligands for the 5-HT1A receptor", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, vol. 7, no. 7, 8 April 1997 (1997-04-08), pages 763 - 768, XP004136126, ISSN: 0960-894X
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