Title:
BGL5 BETA-GLUCOSIDASE AND NUCLEIC ACIDS ENCODING THE SAME
Document Type and Number:
WIPO Patent Application WO2003052054
Kind Code:
A3
Abstract:
The present invention provides a novel beta-glucosidase nucleic acid sequence, designated BGL5, and the corresponding BGL5 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL5, recombinant BGL5 proteins and methods for producing the same.
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Inventors:
DUNN-COLEMAN NIGEL (US)
WARD MICHAEL (US)
YAO JIAN (US)
GOEDEGEBUUR FRITS (NL)
WARD MICHAEL (US)
YAO JIAN (US)
GOEDEGEBUUR FRITS (NL)
Application Number:
PCT/US2002/034764
Publication Date:
December 18, 2003
Filing Date:
October 30, 2002
Export Citation:
Assignee:
GENENCOR INT (US)
DUNN-COLEMAN NIGEL (US)
WARD MICHAEL (US)
YAO JIAN (US)
GOEDEGEBUUR FRITS (NL)
DUNN-COLEMAN NIGEL (US)
WARD MICHAEL (US)
YAO JIAN (US)
GOEDEGEBUUR FRITS (NL)
International Classes:
D06L4/40; C11D3/386; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/24; C12N9/42; C12N15/09; C12P7/06; (IPC1-7): C12P21/06; C12N9/00; C12N9/24; C12N9/42; C12N1/20; C12N15/00; C07H21/04; C11D00/00
Other References:
TAKASHIMA S. ET AL.: "Molecular cloning and expression of the novel fungal beta-glucosidase genes from H.grisea and T.reesei", J. BIOCHEM., vol. 125, January 1999 (1999-01-01), pages 728 - 736, XP002964031
SALOHEIMO M. ET AL.: "Enzymatic properties and intracellular localization of the novel T.reesei beta-glucosidase bglII (cella 1A)", APPL. ENVIRON. MICROBIOL., vol. 68, no. 9, September 2002 (2002-09-01), pages 4546 - 4553, XP002967101
SAWKAR A.R. ET AL.: "Chemical chaperosnes increase the cellular activity of N307S beta-glucosidase: a therapeutic strategy for Gaucher disease", PROC. NATL. ACAD. SCI. USA, vol. 99, no. 24, 26 November 2002 (2002-11-26), pages 15428 - 15433, XP002967102
BELANCIC A. ET AL.: "Beta-glucosidase from the grape native yeast D. varnrijiae: purification, characterization and its effect on nonoterpene content of muscat grape juice", J. AGRIC. FOOD CHEM., vol. 51, no. 5, 26 February 2003 (2003-02-26), pages 1453 - 1459, XP002967103
SALOHEIMO M. ET AL.: "Enzymatic properties and intracellular localization of the novel T.reesei beta-glucosidase bglII (cella 1A)", APPL. ENVIRON. MICROBIOL., vol. 68, no. 9, September 2002 (2002-09-01), pages 4546 - 4553, XP002967101
SAWKAR A.R. ET AL.: "Chemical chaperosnes increase the cellular activity of N307S beta-glucosidase: a therapeutic strategy for Gaucher disease", PROC. NATL. ACAD. SCI. USA, vol. 99, no. 24, 26 November 2002 (2002-11-26), pages 15428 - 15433, XP002967102
BELANCIC A. ET AL.: "Beta-glucosidase from the grape native yeast D. varnrijiae: purification, characterization and its effect on nonoterpene content of muscat grape juice", J. AGRIC. FOOD CHEM., vol. 51, no. 5, 26 February 2003 (2003-02-26), pages 1453 - 1459, XP002967103
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