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Title:
BHK21 CELL POPULATION INNATE IMMUNE SYSTEM OF WHICH IS REMODELED AND APPLICATION THEREOF IN ENHANCING CELL CLONE VIRUS PROLIFERATION
Document Type and Number:
WIPO Patent Application WO/2020/034584
Kind Code:
A1
Abstract:
Provided is a method for enhancing virus proliferation, and a BHK21 cell population the innate immune system of which is remodeled is constructed, being used for virus proliferation. The present method opens up new ideas for virus proliferation, expands the application range of BHK21 cells, and lays a solid foundation for the development of vaccines capable of preventing and treating viruses.

Inventors:
FENG LEI (CN)
CHEN LI (CN)
YUN JUNWEN (CN)
Application Number:
PCT/CN2019/072274
Publication Date:
February 20, 2020
Filing Date:
January 18, 2019
Export Citation:
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Assignee:
JIANGSU ACAD AGRICULTURAL SCI (CN)
International Classes:
C12N5/10; C12N7/00; C12N15/85; C12N15/90
Domestic Patent References:
WO2009086215A22009-07-09
Foreign References:
CN108893450A2018-11-27
CN108611351A2018-10-02
CN107557340A2018-01-09
CN105026555A2015-11-04
CN105121634A2015-12-02
EP2484765A12012-08-08
CN102220289A2011-10-19
CN105886530A2016-08-24
Other References:
WU, W. L. ET AL.: "Development of improved vaccine cell lines against rotavirus", SCIENTIFIC DATA, vol. 4, no. 1, 1 March 2017 (2017-03-01), pages 1 - 12, XP055612777
Attorney, Agent or Firm:
JW IP LAW FIRM (CN)
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