Title:
BIALLELIC MARKERS OF D-AMINO ACID OXIDASE AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2003050303
Kind Code:
A3
Abstract:
The invention concerns the human DAO gene, polynucleotides, and biallelic markers. The invention also concerns the association established between schizophrenia and the biallelic markers. The invention provides means to determine the predisposition of individuals to schizophrenia or related CNS disorder, as well as means for the disease diagnosis and prognosis.
Inventors:
COHEN DANIEL (FR)
CHUMAKOV ILYA (FR)
CHUMAKOV ILYA (FR)
Application Number:
PCT/IB2002/004811
Publication Date:
December 24, 2003
Filing Date:
October 29, 2002
Export Citation:
Assignee:
GENSET SA (FR)
COHEN DANIEL (FR)
CHUMAKOV ILYA (FR)
COHEN DANIEL (FR)
CHUMAKOV ILYA (FR)
International Classes:
C12Q1/68; C12N15/09; (IPC1-7): C12Q1/68
Domestic Patent References:
| WO2000058510A2 | 2000-10-05 | |||
| WO2002066672A2 | 2002-08-29 |
Other References:
DATABASE NCBI [online] 7 June 2001 (2001-06-07), XP002257893, retrieved from SNP accession no. ss3031699 Database accession no. rs2111902
BLOUIN J-L ET AL: "SCHIZOPHRENIA SUSCEPTIBILITY LOCI ON CHROMOSOMES 13Q32 AND 8P21", NATURE GENETICS, NEW YORK, NY, US, vol. 20, no. 1, September 1998 (1998-09-01), pages 70 - 73, XP000944108, ISSN: 1061-4036
CHUMAKOV I ET AL: "Genetic and physiological data implicating in the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 99, no. 21, 15 October 2002 (2002-10-15), pages 13675 - 13680, XP002967443, ISSN: 0027-8424
BLOUIN J-L ET AL: "SCHIZOPHRENIA SUSCEPTIBILITY LOCI ON CHROMOSOMES 13Q32 AND 8P21", NATURE GENETICS, NEW YORK, NY, US, vol. 20, no. 1, September 1998 (1998-09-01), pages 70 - 73, XP000944108, ISSN: 1061-4036
CHUMAKOV I ET AL: "Genetic and physiological data implicating in the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 99, no. 21, 15 October 2002 (2002-10-15), pages 13675 - 13680, XP002967443, ISSN: 0027-8424
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