Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
BIARYL DERIVATIVE AS GPR120 AGONIST
Document Type and Number:
WIPO Patent Application WO/2016/105118
Kind Code:
A3
Abstract:
The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

Inventors:
KIM YOUNG KWAN (KR)
PARK SANG YUN (KR)
JOO HYUN WOO (KR)
CHOI EUN SIL (KR)
PAEK SEUNG YUP (KR)
KANG SEUNG WAN (KR)
KIM BYUNG GYU (KR)
LEE CHANG SEOK (KR)
KIM SUNG WOOK (KR)
LEE SANG DAE (KR)
Application Number:
KR2015/014178
Publication Date:
October 13, 2016
Filing Date:
December 23, 2015
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
LG LIFE SCIENCES LTD (KR)
International Classes:
C07D401/04; A61K31/4725; A61P3/04; A61P3/10
Domestic Patent References:
WO2011159297A12011-12-22
WO2013139341A12013-09-26
WO2013185766A12013-12-19
WO2014059232A22014-04-17
WO2014209034A12014-12-31
Foreign References:
KR20090113382A2009-10-30
Other References:
See also references of EP 3239143A4
Attorney, Agent or Firm:
CHOI, Kyu Pal (23 Gangnam-daero 84-gil,Gangnam-gu, Seoul 137-810, KR)
Download PDF: