Title:
BIARYL UREA DERIVATIVE OR SALT THEREOF, AND MANUFACTURING AND APPLICATION OF SAME
Document Type and Number:
WIPO Patent Application WO/2017/219935
Kind Code:
A1
Abstract:
The present invention discloses a biaryl urea RORγt inhibitor, and specifically relates to a biaryl urea derivative, as represented by formula I, with an RORγt inhibiting activity, and a manufacturing method thereof, and a pharmaceutical composition comprising the compound. Further disclosed is an application of the compound for treating an RORγt-related disease.
Inventors:
WANG YONGHUI (CN)
HUANG YAFEI (CN)
YU FAZHI (CN)
TANG TING (CN)
HUANG YAFEI (CN)
YU FAZHI (CN)
TANG TING (CN)
Application Number:
PCT/CN2017/088956
Publication Date:
December 28, 2017
Filing Date:
June 19, 2017
Export Citation:
Assignee:
UNIV FUDAN (CN)
International Classes:
C07C317/32; A61K31/17; A61K31/18; A61P1/00; A61P11/06; A61P17/06; A61P19/02; A61P29/00; C07C311/47; C07C311/51; C07C381/10; C07D213/71
Domestic Patent References:
| WO1999038846A1 | 1999-08-05 | |||
| WO2003000245A1 | 2003-01-03 |
Foreign References:
| CN102378753A | 2012-03-14 | |||
| CN1714076A | 2005-12-28 | |||
| CN1678573A | 2005-10-05 | |||
| CN1539816A | 2004-10-27 | |||
| EP2990057A1 | 2016-03-02 |
Other References:
DATABASE CAS 13 April 2007 (2007-04-13), retrieved from STN Database accession no. 27.0033
See also references of EP 3476829A4
See also references of EP 3476829A4
Attorney, Agent or Firm:
SUNRAY INTELLECTUAL PROPERTY ATTORNEYS (CN)
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