Title:
BIARYLETHER IMIDAZOPYRAZINE BTK INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2016/106652
Kind Code:
A1
Abstract:
Provided are Bruton's Tyrosine Kinase (Btk) inhibitor compounds of Formula I, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions comprising these compounds and their use in therapy. In particular, provided is the use of Btk inhibitor compounds of Formula I in the treatment of Btk mediated disorders.
Inventors:
LIU JIAN (US)
KOZLOWSKI JOSEPH A (US)
BOGA SOBHANA BABU (US)
GAO XIAOLEI (US)
GUIADEEN DEODIALSINGH (US)
WANG JYHSHING (US)
LIU SHILAN (CN)
KOZLOWSKI JOSEPH A (US)
BOGA SOBHANA BABU (US)
GAO XIAOLEI (US)
GUIADEEN DEODIALSINGH (US)
WANG JYHSHING (US)
LIU SHILAN (CN)
Application Number:
PCT/CN2014/095826
Publication Date:
July 07, 2016
Filing Date:
December 31, 2014
Export Citation:
Assignee:
MERCK SHARP & DOHME (US)
LIU JIAN (US)
KOZLOWSKI JOSEPH A (US)
BOGA SOBHANA BABU (US)
GAO XIAOLEI (US)
GUIADEEN DEODIALSINGH (US)
WANG JYHSHING (US)
LIU SHILAN (CN)
LIU JIAN (US)
KOZLOWSKI JOSEPH A (US)
BOGA SOBHANA BABU (US)
GAO XIAOLEI (US)
GUIADEEN DEODIALSINGH (US)
WANG JYHSHING (US)
LIU SHILAN (CN)
International Classes:
C07D487/04; A61K31/4985; A61P19/08; A61P29/00; A61P31/00; A61P35/00; A61P37/00; C07D497/02
Domestic Patent References:
| WO2014113932A1 | 2014-07-31 | |||
| WO2013010380A1 | 2013-01-24 | |||
| WO2005037836A2 | 2005-04-28 |
Foreign References:
| US20090286768A1 | 2009-11-19 |
Attorney, Agent or Firm:
WU, FENG & ZHANG CO. (Tower BBeijing Aerospace Cpmiec Building,No. 30 Haidian South Roa, Haidian District Beijing 0, CN)
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