Title:
BICYCLIC AMINO DERIVATIVES AND PGD2 ANTAGONIST CONTAINING THE SAME
Document Type and Number:
WIPO Patent Application WO/1997/000853
Kind Code:
A1
Abstract:
Compounds of general formula (I), salts thereof or hydrates thereof wherein (a) represents (b) or (c), for example, the compounds (d) and (e), which are useful as a PGD2 antagonist and thus usable in, for example, a remedy for systemic mastocytosis or systemic mast cell activation disorders, a drug for bronchoconstriction, an antiasthmatic, a drug for allergic rhinitis agent, a drug for allergic conjunctivitis, a drug for urticaria, a remedy for ischemia reflow disorders or an antiinflammatory agent. It is particularly useful in the treatment of nasal occlusion.
Inventors:
OHTANI MITSUAKI (JP)
ARIMURA AKINORI (JP)
TSURI TATSUO (JP)
KISHINO JUNJI (JP)
HONMA TSUNETOSHI (JP)
ARIMURA AKINORI (JP)
TSURI TATSUO (JP)
KISHINO JUNJI (JP)
HONMA TSUNETOSHI (JP)
Application Number:
PCT/JP1996/001685
Publication Date:
January 09, 1997
Filing Date:
June 19, 1996
Export Citation:
Assignee:
SHIONOGI & CO (JP)
OHTANI MITSUAKI (JP)
ARIMURA AKINORI (JP)
TSURI TATSUO (JP)
KISHINO JUNJI (JP)
HONMA TSUNETOSHI (JP)
OHTANI MITSUAKI (JP)
ARIMURA AKINORI (JP)
TSURI TATSUO (JP)
KISHINO JUNJI (JP)
HONMA TSUNETOSHI (JP)
International Classes:
A61K31/557; C07C233/52; C07C233/63; C07C233/74; C07C233/81; C07C233/84; C07C235/22; C07C235/36; C07C235/42; C07C235/54; C07C235/84; C07C237/38; C07C237/42; C07C245/08; C07C251/48; C07C251/86; C07C255/57; C07C271/24; C07C275/42; C07C281/14; C07C309/65; C07C311/13; C07C311/20; C07C311/29; C07C311/37; C07C311/43; C07C311/46; C07C311/51; C07C317/44; C07C323/62; C07C337/08; C07D207/34; C07D209/08; C07D209/10; C07D209/12; C07D209/42; C07D209/88; C07D213/56; C07D213/81; C07D215/36; C07D221/12; C07D235/06; C07D257/04; C07D261/18; C07D263/57; C07D271/06; C07D271/107; C07D275/03; C07D277/20; C07D277/56; C07D279/20; C07D279/22; C07D285/06; C07D285/12; C07D295/192; C07D307/68; C07D307/84; C07D307/91; C07D311/12; C07D311/24; C07D311/82; C07D313/14; C07D317/48; C07D319/24; C07D333/18; C07D333/24; C07D333/32; C07D333/34; C07D333/36; C07D333/38; C07D333/62; C07D333/68; C07D333/76; C07D333/78; C07D337/14; C07D521/00; C07F9/535; C07D263/56; C07D271/10; C07D275/02; (IPC1-7): C07C233/52; C07C233/84; C07C271/24; C07C311/06; C07C311/11; C07C311/13; C07C311/19; C07D493/08; C07D495/08; A61K31/16; A61K31/18; A61K31/27; A61K31/33; A61K31/34; A61K31/35; A61K31/38
Foreign References:
JPH06279395A | 1994-10-04 | |||
JPH02180862A | 1990-07-13 | |||
JPS63139161A | 1988-06-10 | |||
JPS60178876A | 1985-09-12 |
Other References:
See also references of EP 0837052A4
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