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Title:
BICYCLIC COMPOUNDS HAVING BRADYKININ RECEPTORS AFFINITY AND PHARMACEUTICAL COMPOSITIONS THEREOF
Document Type and Number:
WIPO Patent Application WO2004092116
Kind Code:
A8
Abstract:
Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Inventors:
GRONEBERG ROBERT D (US)
ASKEW BEN (US)
D AMICO DERIN C (US)
ZHAN JAMES (US)
TORO ANDRAS (US)
SUZUKI HIDEO (US)
MARESKA DAVID A (US)
HAN NIANH (US)
FOTSCH CHRISTOPHER H (US)
LIU QINGLAN (US)
RIAHI BABAK (US)
YANG KEVIN (US)
LI AIWAN (US)
YUAN CHESTER (US)
BISWAS KAUSTAV (US)
HARRIED SCOTT (US)
NGUYEN TOM (US)
QIAN WENYUAN (US)
CHEN JIAN J (US)
NOMAK RANA (US)
Application Number:
PCT/US2004/011105
Publication Date:
May 06, 2005
Filing Date:
April 12, 2004
Export Citation:
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Assignee:
AMGEN INC (US)
ARRAY BIOPHARMA INC (US)
GRONEBERG ROBERT D (US)
ASKEW BEN (US)
D AMICO DERIN C (US)
ZHAN JAMES (US)
TORO ANDRAS (US)
SUZUKI HIDEO (US)
MARESKA DAVID A (US)
HAN NIANH (US)
FOTSCH CHRISTOPHER H (US)
LIU QINGLAN (US)
RIAHI BABAK (US)
YANG KEVIN (US)
LI AIWAN (US)
YUAN CHESTER (US)
BISWAS KAUSTAV (US)
HARRIED SCOTT (US)
NGUYEN TOM (US)
QIAN WENYUAN (US)
CHEN JIAN J (US)
NOMAK RANA (US)
International Classes:
A61K31/18; A61K31/277; A61K31/405; A61K31/47; A61P25/04; A61P29/00; C07C311/19; C07C311/29; C07D205/04; C07D207/12; C07D207/16; C07D207/20; C07D209/14; C07D209/16; C07D209/40; C07D209/52; C07D211/38; C07D211/44; C07D211/46; C07D211/60; C07D211/70; C07D213/42; C07D213/56; C07D213/64; C07D215/38; C07D215/40; C07D215/42; C07D217/22; C07D233/54; C07D239/74; C07D271/08; C07D277/64; C07D279/02; C07D285/14; C07D295/125; C07D295/13; C07D295/135; C07D307/14; C07D307/28; C07D307/79; C07D307/81; C07D311/68; C07D317/58; C07D333/20; C07D333/24; C07D333/58; C07D333/62; C07D405/04; C07D405/06; C07D405/12; C07D407/06; C07D407/12; C07D409/06; C07D409/12; C07D413/12; C07D417/12; C07D471/04; C07D487/08; (IPC1-7): C07C311/18; A61K31/18; A61K31/33; A61K31/34; A61P25/04; A61P29/00; C07D279/00; C07D295/135; C07D311/68; C07D409/12
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