BICYCLOLACTAM COMPOUNDS, USE OF THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE SAME

Title:

BICYCLOLACTAM COMPOUNDS, USE OF THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE SAME

Document Type and Number:

WIPO Patent Application WO/1996/041796

Kind Code:

A1

Abstract:

Bicyclolactam compounds represented by general formula (1) are useful as the active ingredient of medicines having an excellent anxiolytic effect and a high safety with little side effects such as a hypnotic effect, a muscle relaxing effect, a sedative effect, etc. In said formula, R represents oxo or -OR1 (wherein R1 represents hydrogen or acyl); A represents one of the following groups (2) and (3); Q represents hydrogen or lower alkyl; l is 1 or 2, m is 0 or 1; and n is 0, 1 or 2, provided that m and n are not 0 at the same time; R2 represents optionally substituted benzoyl.

Inventors:

OGAWA KAZUO (JP)
YAMAWAKI ICHIRO (JP)
KANEDA MANABU (JP)
ARIMA TAKASHI (JP)

Application Number:

PCT/JP1996/001565

Publication Date:

December 27, 1996

Filing Date:

June 07, 1996

Export Citation:

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Assignee:

TAIHO PHARMACEUTICAL CO LTD (JP)
OGAWA KAZUO (JP)
YAMAWAKI ICHIRO (JP)
KANEDA MANABU (JP)
ARIMA TAKASHI (JP)

International Classes:

A61K31/40; A61K31/403; A61K31/4035; A61K31/404; A61K31/435; A61K31/47; A61K31/472; C07D215/22; A61K31/473; A61K31/55; A61P25/20; A61P25/22; C07D209/34; C07D209/46; C07D209/52; C07D215/227; C07D217/24; C07D221/04; C07D221/16; C07D223/14; C07D223/16; (IPC1-7): C07D209/52; C07D221/04; C07D215/22; A61K31/40; A61K31/435; A61K31/47

Domestic Patent References:

WO1995026187A1	1995-10-05
WO1991011434A1	1991-08-08

Other References: