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Title:
BIFIDOBACTERIUM LONGUM HAVING CEPHALOSPORIN RESISTANCE AND HIGH EXPRESSION OF SIR2 PROTEIN, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/218694
Kind Code:
A1
Abstract:
Provided are a Bifidobacterium longum BL16 having cephalosporin resistance and high expression of Sir2 protein, and application thereof in preparing foods or medicines for anti-aging, enhancing immune function, or regulating intestinal microbiota. The Bifidobacterium longum BL16 having cephalosporin resistance and high expression of Sir2 protein improves the micro-ecological environment of the intestinal tract, removes free radicals from the body, delaying the process of aging of animals, and can also significantly increase the weight of aging organs, maintain the immune function of an organism, and improve disease resistance capability; Therefore the Bifidobacterium longum BL16 having cephalosporin resistance and high expression of Sir2 protein can be used for preparing foods or medicines for anti-aging, enhancing immune function, or regulating intestinal microbiota.

Inventors:
SUN HANXIAO (CN)
GUO QING (CN)
LI SHIYU (CN)
LIU MENGGE (CN)
CHEN LUPING (CN)
HUANG JINQUN (CN)
Application Number:
PCT/CN2017/087285
Publication Date:
December 06, 2018
Filing Date:
June 06, 2017
Export Citation:
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Assignee:
GUANGZHOU HOPBIOYOUTH BIOTECHNOLOGY CO LTD (CN)
International Classes:
C12N1/21; A23L33/135; A23L33/195; A61K35/745; A61P31/04; A61P37/04; A61P39/06; C12R1/01
Foreign References:
CN105039192A2015-11-11
CN105646679A2016-06-08
US20030045482A12003-03-06
JP2008195673A2008-08-28
Other References:
QING, GUO ET AL.: "The NAD+-dependent Deacetylase, Bifidobacterium Longum Sir2 in Response to Oxidative Stress by Deacetylating SigH (sigmaH) and F0X03a in Bifidobacterium longum and HEK293T cell respectively", FREE RADICAL BIOLOGY AND MEDICINE, vol. 108, 12 May 2017 (2017-05-12), XP055553706, ISSN: 0891-5849
Attorney, Agent or Firm:
GUANGZHOU KEYUE I.P. LAW OFFICE (CN)
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