Title:
BINDING AGENT
Document Type and Number:
WIPO Patent Application WO/2017/026505
Kind Code:
A1
Abstract:
In the immobilization of molecular recognition elements on electrodes, there has been a demand for an immobilization method capable of controlling orientation and for a versatile immobilization method. As a reflection of that described above, the purpose of the present invention is to provide a binding agent capable of binding metal, a metal-binding molecular recognition element coupled to the binding agent, a molecular recognition element immobilization electrode, on which the molecular recognition element is immobilized, a method for manufacturing the electrode, a sensor including the electrode, and a method for manufacturing the sensor. The inventors discovered a peptide capable of binding metal (metal-binding peptide), and discovered that the metal binding peptide can be used as a binding agent between protein and metal, and that a metal-binding molecular recognition element can be made by coupling the peptide to a molecular recognition element comprising a protein. Furthermore, it was discovered that, by using the metal-binding molecular recognition element, the molecular recognition element can be immobilized on an electrode in an oriented manner. Furthermore, a method for producing a molecular recognition element immobilization electrode by way of the immobilization method was discovered, thereby completing the present invention.
Inventors:
TAKUMI TAKAFUMI (JP)
IMANAKA HIROYUKI (JP)
IMAMURA KOREYOSHI (JP)
MATOBA HARUKA (JP)
IMANAKA HIROYUKI (JP)
IMAMURA KOREYOSHI (JP)
MATOBA HARUKA (JP)
Application Number:
PCT/JP2016/073537
Publication Date:
February 16, 2017
Filing Date:
August 10, 2016
Export Citation:
Assignee:
IKEDA FOOD RES CO LTD (JP)
International Classes:
G01N33/483; C07K7/06; C07K19/00; C12Q1/00; C12Q1/54; C12N9/04; C12N9/16; C12N9/88; C12N11/14; G01N27/327
Domestic Patent References:
| WO2003025121A2 | 2003-03-27 |
Foreign References:
| JP2014205626A | 2014-10-30 | |||
| US20060246426A1 | 2006-11-02 | |||
| JP2007197435A | 2007-08-09 | |||
| JP2010107491A | 2010-05-13 | |||
| JP2004215514A | 2004-08-05 | |||
| JP2008076388A | 2008-04-03 |
Attorney, Agent or Firm:
ABE Masahiro (JP)
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