Title:
BINDING PROTEINS AGAINST VEGF, PDGF, AND/OR THEIR RECEPTORS
Document Type and Number:
WIPO Patent Application WO/2016/205427
Kind Code:
A3
Abstract:
Binding proteins that bind one or more of VEGF, PDGF and/or their receptors, including antibodies, CDR-grafted antibodies, humanized antibodies, binding fragments, fusion proteins, and bispecific or multispecific proteins thereof are disclosed. Also disclosed are methods of making and using the binding proteins.
Inventors:
GU JIJIE (US)
BOWLEY DIANA (US)
EATON LUCIA (US)
DONG FENG (US)
BENATUIL LORENZO (US)
GHAYUR TARIQ (US)
CHARI RAVI (US)
RIESER MATTHEW (US)
CLABBERS ANCA (US)
BOWLEY DIANA (US)
EATON LUCIA (US)
DONG FENG (US)
BENATUIL LORENZO (US)
GHAYUR TARIQ (US)
CHARI RAVI (US)
RIESER MATTHEW (US)
CLABBERS ANCA (US)
Application Number:
PCT/US2016/037710
Publication Date:
February 09, 2017
Filing Date:
June 15, 2016
Export Citation:
Assignee:
ABBVIE INC (US)
International Classes:
C07K16/24
Domestic Patent References:
| WO2014071074A2 | 2014-05-08 | |||
| WO2005087812A1 | 2005-09-22 |
Other References:
DIGIAMMARINO ENRICO ET AL: "Design and generation of DVD-Ig(TM) molecules for dual-specific targeting", METHODS IN MOLECULAR BIOLOGY (CLIFTON, N.J.)UNITED STATES2010,, vol. 899, 1 January 2012 (2012-01-01), pages 145 - 156, XP009169361, ISSN: 1940-6029, DOI: 10.1007/978-1-61779-921-1_9
ROLAND KONTERMANN: "Dual targeting strategies with bispecific antibodies", MABS, LANDES BIOSCIENCE, US, vol. 4, no. 2, 1 March 2012 (2012-03-01), pages 182 - 197, XP009160769, ISSN: 1942-0870, DOI: 10.4161/MABS.4.2.19000
ROLAND KONTERMANN: "Dual targeting strategies with bispecific antibodies", MABS, LANDES BIOSCIENCE, US, vol. 4, no. 2, 1 March 2012 (2012-03-01), pages 182 - 197, XP009160769, ISSN: 1942-0870, DOI: 10.4161/MABS.4.2.19000
Attorney, Agent or Firm:
MCDONELL, Leslie A. et al. (US)
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