Title:
BIOABSORBABLE MEDICAL MATERIAL
Document Type and Number:
WIPO Patent Application WO/2021/201150
Kind Code:
A1
Abstract:
The present invention provides a bioabsorbable medical material which has close adhesiveness to a biological tissue and is improved in degradability. The bioabsorbable medical material according to the present invention comprises a crosslinked polymer material capable of forming a specific shape and a collapse delay material supported on the crosslinked polymer material. The crosslinked polymer material has such degradability in water that the degradation of the crosslinked polymer material can be suppressed in the presence of an acid, and the collapse delay material can release an acid until day-7 at a rate of 0.5 mol%/day upon the contact with water at 37°C.
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Inventors:
TAKATSUJI KAZUHISA (JP)
FUJIEDA AYAKO (JP)
GOTO SUMIE (JP)
MACHI YOSHIKI (JP)
HIRATA JUNYA (JP)
SHIMADA HIRONAO (JP)
HIRATA RIEKO (JP)
SEKINE FUJIO (JP)
YAMASHITA YUSUKE (JP)
SATO TAKEHIRO (JP)
AKANUMA MIE (JP)
FUKUMOTO TAKUMI (JP)
FUJIEDA AYAKO (JP)
GOTO SUMIE (JP)
MACHI YOSHIKI (JP)
HIRATA JUNYA (JP)
SHIMADA HIRONAO (JP)
HIRATA RIEKO (JP)
SEKINE FUJIO (JP)
YAMASHITA YUSUKE (JP)
SATO TAKEHIRO (JP)
AKANUMA MIE (JP)
FUKUMOTO TAKUMI (JP)
Application Number:
PCT/JP2021/013973
Publication Date:
October 07, 2021
Filing Date:
March 31, 2021
Export Citation:
Assignee:
KUREHA CORP (JP)
UNIV KOBE NAT UNIV CORP (JP)
UNIV KOBE NAT UNIV CORP (JP)
International Classes:
A61L15/00; A61K47/34; A61K47/36; A61K47/38; A61L31/06; A61L31/10; A61L31/12; A61L31/14
Domestic Patent References:
| WO2016136884A1 | 2016-09-01 |
Foreign References:
| US20020071855A1 | 2002-06-13 | |||
| JP2008155014A | 2008-07-10 | |||
| JP2003523237A | 2003-08-05 | |||
| JP2003518167A | 2003-06-03 | |||
| JPH05124968A | 1993-05-21 | |||
| JPH02138346A | 1990-05-28 | |||
| JP2004051531A | 2004-02-19 | |||
| JPH08208706A | 1996-08-13 | |||
| CN105194739A | 2015-12-30 |
Other References:
KANG, SUN-WOONG ET AL.: "PLGA Microspheres in Hyaluronic Acid Gel as a Potential Bulking Agent for Urologic and Dermatologic Injection Therapies", JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, vol. 15, no. 3, June 2005 (2005-06-01), pages 510 - 518, XP008122627
LIN XUNXUN, WANG WENBO, ZHANG WENJIE, ZHANG ZHIYONG, ZHOU GUANGDONG, CAO YILIN, LIU WEI: "Hyaluronic Acid Coating Enhances Biocompatibility of Nonwoven PGA Scaffold and Cartilage Formation", TISSUE ENGINEERING. PART C, METHODS DEC 2008, MARY ANN LIEBERT, INC. PUBLISHERS, US, vol. 23, no. 2, 1 February 2017 (2017-02-01), US , pages 86 - 97, XP055924351, ISSN: 1937-3384, DOI: 10.1089/ten.tec.2016.0373
R. V. SPARERN. EKWURIBEA. G. WALTON: "Controlled Release Delivery Systems", 1983, DEKKER, article "Controlled release from glycosaminoglycan drug complexes", pages: 107 - 119
See also references of EP 4129349A4
LIN XUNXUN, WANG WENBO, ZHANG WENJIE, ZHANG ZHIYONG, ZHOU GUANGDONG, CAO YILIN, LIU WEI: "Hyaluronic Acid Coating Enhances Biocompatibility of Nonwoven PGA Scaffold and Cartilage Formation", TISSUE ENGINEERING. PART C, METHODS DEC 2008, MARY ANN LIEBERT, INC. PUBLISHERS, US, vol. 23, no. 2, 1 February 2017 (2017-02-01), US , pages 86 - 97, XP055924351, ISSN: 1937-3384, DOI: 10.1089/ten.tec.2016.0373
R. V. SPARERN. EKWURIBEA. G. WALTON: "Controlled Release Delivery Systems", 1983, DEKKER, article "Controlled release from glycosaminoglycan drug complexes", pages: 107 - 119
See also references of EP 4129349A4
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (JP)
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