Title:
BIOABSORBABLE PLASTIC INSTRUMENTS FOR MEDICAL USE
Document Type and Number:
WIPO Patent Application WO/2004/000377
Kind Code:
A1
Abstract:
Bioabsorbable polymers employed as medical materials such as vascular stents and sutures have almost constant dynamic properties (tensile strength, etc.) and degradation speed due to absorption. In case of improving these dynamic properties, then these materials become fragile and the degradation speed is lowered. In case of elevating the degradation speed, then the dynamic properties are worsened and, as a result, there arises a problem that the purpose and site of using are restricted. Under these circumstances, a bioabsorbable polymer is copolymerized with a cyclic depsipeptide to give a copolymer having the ring−opening copolymerized depsipeptide. Thus, the dynamic properties and degradation speed can be controlled depending on the content of the depsipeptide.
Inventors:
SHIRAHAMA HIROYUKI (JP)
MIYAZAKI MASAMITSU (JP)
FUKUCHI MIKIO (JP)
MIYAZAKI MASAMITSU (JP)
FUKUCHI MIKIO (JP)
Application Number:
PCT/JP2002/006331
Publication Date:
December 31, 2003
Filing Date:
June 25, 2002
Export Citation:
Assignee:
GOODMAN CO LTD (JP)
SHIRAHAMA HIROYUKI (JP)
MIYAZAKI MASAMITSU (JP)
FUKUCHI MIKIO (JP)
SHIRAHAMA HIROYUKI (JP)
MIYAZAKI MASAMITSU (JP)
FUKUCHI MIKIO (JP)
International Classes:
A61L17/10; A61L31/06; (IPC1-7): A61L27/18; A61L27/58; A61L29/06; A61L29/08; A61L29/18
Domestic Patent References:
| WO1999032536A1 | 1999-07-01 |
Foreign References:
| EP0086613A1 | 1983-08-24 | |||
| EP0322154A2 | 1989-06-28 | |||
| JPH10155896A | 1998-06-16 | |||
| EP0528039A1 | 1993-02-24 | |||
| EP1110561A2 | 2001-06-27 | |||
| JPH10127754A | 1998-05-19 |
Other References:
SHIRAHAMA H. ET AL.: "Synthesis and enzymatic degradation of optically active depsipeptide copolymers", JOURNAL OF BIOMATERIALS SCIENCE, POLYMER EDITION, vol. 10, no. 6, 1999, pages 621 - 639, XP002956695
SHIRAHAMA H. ET AL.: "Highly biodegradable copolymers composed of chiral depsipeptide and L-lactide units with favorable physical properties", JOURNAL OF POLYMER SCIENCE, PART A: POLYMER CHEMISTRY, vol. 40, no. 3, 2001, pages 302 - 316, XP002956696
SHIRAHAMA H. ET AL.: "Highly biodegradable copolymers composed of chiral depsipeptide and L-lactide units with favorable physical properties", JOURNAL OF POLYMER SCIENCE, PART A: POLYMER CHEMISTRY, vol. 40, no. 3, 2001, pages 302 - 316, XP002956696
Attorney, Agent or Firm:
Kanakura, Kyoji (Shinbashi 1-chome Minato-ku, Tokyo, JP)
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