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Title:
BIOCOMPATIBLE LONG-FIBER NONWOVEN FABRIC, PRODUCTION METHOD THEREFOR, THREE-DIMENSIONAL SCAFFOLD FOR CELL CULTURING, AND CELL CULTURING METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2018/235745
Kind Code:
A1
Abstract:
The present invention pertains to a biocompatible long-fiber nonwoven fabric including, as the main component, a biocompatible polymer, wherein biocompatible long fibers constituting the biocompatible long-fiber nonwoven fabric have a fiber diameter that varies in the longitudinal direction, have fiber intersections being partially welded thereto, do not sag even when wet, and become transparent when wet. This biocompatible long-fiber nonwoven fabric can be prepared by extruding, into the air, a spinning liquid containing a biocompatible polymer through a nozzle discharge port 3, jetting a pressure liquid 7 forward from a fluid jet orifice 5 that is not in contact with the nozzle discharge port 3 and that is located rearward of the nozzle discharge port 3, letting the extruded spinning liquid accompany the pressure fluid 7 to undergo fiber formation, and then accumulating long fibers 8 resulting from the fiber formation into a long-fiber nonwoven fabric 9. With such a configuration, the present invention provides: a biocompatible long-fiber nonwoven fabric having high forming stability and formability useful for medical applications, cell culturing scaffolds, and the like; a production method therefor; a three-dimensional scaffold for cell culturing; and a cell culturing method using same.

Inventors:
TABATA Yasuhiko (3-8-16, Biwadai Uji-cit, Kyoto 24, 〒6110024, JP)
UESUGI Shoji
OI Masao
SAOTOME Toshiki
NAKAMURA Koichiro
Application Number:
JP2018/022988
Publication Date:
December 27, 2018
Filing Date:
June 15, 2018
Export Citation:
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Assignee:
THE JAPAN WOOL TEXTILE CO., LTD. (47 Akashimachi, Chuo-ku Kobe-sh, Hyogo 37, 〒6500037, JP)
TABATA Yasuhiko (3-8-16, Biwadai Uji-cit, Kyoto 24, 〒6110024, JP)
International Classes:
D04H3/16; A61L27/22; A61L27/58; C12M1/00; C12N5/071; D04H3/015; D04H3/016
Domestic Patent References:
WO2014196549A12014-12-11
WO2014192803A12014-12-04
Foreign References:
JP2003125757A2003-05-07
JP2015501343A2015-01-15
Attorney, Agent or Firm:
IKEUCHI SATO & PARTNER PATENT ATTORNEYS (26th Floor, OAP TOWER 8-30, Tenmabashi 1-chome, Kita-ku, Osaka-sh, Osaka 26, 〒5306026, JP)
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