Title:
BIODEGRADABLE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2013/064059
Kind Code:
A8
Abstract:
Provided is a medical adhesive with good biodegradable performance capable of cross-linking and copolymerizing, comprising a mono-α-cyanoacrylate and a bis-α-cyanoacrylic acid diol ester monomer molecule. The olefinic bonds in the mono-α-cyanoacrylate structure are polymerized in the presence of infinitesimal anions to form a solid 3D type high polymer; the 3D type high polymer is provided with degradation sites on the web-like backbone chain, with clear degradation path and absorbable degradation products. The medical adhesive can be used for wound adhesive, large area wound hemostasia, and visceral and soft tissue wound closure. Furthermore, the medical adhesive also has the potential to be used as a tissue engineering material.
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Inventors:
LIU KELIANG (CN)
XU LIANG (CN)
ZHANG QINGSONG (CN)
CAI DAZHEN (CN)
MENG QINGBIN (CN)
XU LIANG (CN)
ZHANG QINGSONG (CN)
CAI DAZHEN (CN)
MENG QINGBIN (CN)
Application Number:
PCT/CN2012/083787
Publication Date:
June 05, 2014
Filing Date:
October 31, 2012
Export Citation:
Assignee:
INST PHARM & TOXICOLOGY AMMS (CN)
CHENGDU YIPING MEDICAL SCIENCE & TECHNOLOGY CO LTD (CN)
CHENGDU YIPING MEDICAL SCIENCE & TECHNOLOGY CO LTD (CN)
International Classes:
A61L24/06; C08F222/32; C08L35/04; C09J4/04; C09J135/04
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (Vantone New World Plaza2 Fuchengmenwai Street, Xicheng District, Beijing 7, CN)
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