Title:
BIOLOGICAL MEMBRANE-INTRINSIC VIRUS-LIKE PARTICLE, AND METHOD FOR PRODUCTION THEREOF
Document Type and Number:
WIPO Patent Application WO/2009/066802
Kind Code:
A1
Abstract:
Disclosed is a method which can produce a genomic-DNA-free, pure virus-like
particle reliably and at a high purity, and which can control the type, state of
occurrence, configuration or the like of a molecule in a capsid readily. Also
disclosed is a virus-like particle which is characterized by comprising (1)
a capsid-forming protein, (2) a penton protein, and (3) at least one membrane-forming
protein, all of which are proteins constituting a membrane-intrinsic virus.
Inventors:
KANDA HIROMI (JP)
MATSUMOTO OSAMU (JP)
SHIBA TADAYOSHI (JP)
KIMURA TAKETOSHI (JP)
TAKAMATSU NOBUHIKO (JP)
KIKKOU TATSUHIKO (JP)
ITO MICHIHIKO (JP)
IWABUCHI SHINICHIRO (JP)
MATSUMOTO OSAMU (JP)
SHIBA TADAYOSHI (JP)
KIMURA TAKETOSHI (JP)
TAKAMATSU NOBUHIKO (JP)
KIKKOU TATSUHIKO (JP)
ITO MICHIHIKO (JP)
IWABUCHI SHINICHIRO (JP)
Application Number:
PCT/JP2008/071760
Publication Date:
May 28, 2009
Filing Date:
November 25, 2008
Export Citation:
Assignee:
SCHOOL JURIDICAL PERSON KITASA (JP)
SCHOOL JURIDICAL PERSON KAKE E (JP)
KANDA HIROMI (JP)
MATSUMOTO OSAMU (JP)
SHIBA TADAYOSHI (JP)
KIMURA TAKETOSHI (JP)
TAKAMATSU NOBUHIKO (JP)
KIKKOU TATSUHIKO (JP)
ITO MICHIHIKO (JP)
IWABUCHI SHINICHIRO (JP)
SCHOOL JURIDICAL PERSON KAKE E (JP)
KANDA HIROMI (JP)
MATSUMOTO OSAMU (JP)
SHIBA TADAYOSHI (JP)
KIMURA TAKETOSHI (JP)
TAKAMATSU NOBUHIKO (JP)
KIKKOU TATSUHIKO (JP)
ITO MICHIHIKO (JP)
IWABUCHI SHINICHIRO (JP)
International Classes:
C12N15/09; C12N7/00; C12N7/02
Other References:
HIROMI KANDA: "Maku Kantsugata Juyotai Tanpakushitsu no Seitaimaku Naizaisei Virus Capsid o Mochiita Ippanteki X-sen Kessho Kaisekiho no Kakuritsu", NEW ENERGY AND INDUSTRIAL TECHNOLOGY DEVELOPMENT ORGANIZATION HEISEI 17 NENDO SANGYO GIJUTSU KENKYU JOSEI JIGYO KENKYU SEIKA HOKOKUSHO, Retrieved from the Internet [retrieved on 20070517]
HIROMI KANDA: "Maku Kantsugata Juyotai Tanpakushitsu no Seitaimaku Naizaisei Virus Capsid o Mochiita Ippanteki X-sen Kessho Kaisekiho no Kakuritsu", NEW ENERGY AND INDUSTRIAL TECHNOLOGY DEVELOPMENT ORGANIZATION HEISEI 18 NENDO SANGYO GIJUTSU KENKYU JOSEI JIGYO KENKYU SEIKA HOKOKUSHO, Retrieved from the Internet [retrieved on 20080516]
"Dai 30 Kai Annual Meeting of the Molecular Biology Society of Japan, Dai 80 Kai The Japanese Biochemical Society Taikai Godo Taikai Koen Yoshishu", 25 November 2007, article HIROMI KANDA ET AL.: "GPCR Kozo Kaiseki no Tameno Seitaimaku Naizaisei PR772 Phage Ryushi no Saikoseikei no Kakuritsu", pages: 711
ABRESCIA, N. G. A. ET AL.: "Insights into assembly from structural analysis of bacteriophage PRD1", NATURE, vol. 432, 2004, pages 68 - 74
HIROMI KANDA: "Maku Kantsugata Juyotai Tanpakushitsu no Seitaimaku Naizaisei Virus Capsid o Mochiita Ippanteki X-sen Kessho Kaisekiho no Kakuritsu", NEW ENERGY AND INDUSTRIAL TECHNOLOGY DEVELOPMENT ORGANIZATION HEISEI 18 NENDO SANGYO GIJUTSU KENKYU JOSEI JIGYO KENKYU SEIKA HOKOKUSHO, Retrieved from the Internet
"Dai 30 Kai Annual Meeting of the Molecular Biology Society of Japan, Dai 80 Kai The Japanese Biochemical Society Taikai Godo Taikai Koen Yoshishu", 25 November 2007, article HIROMI KANDA ET AL.: "GPCR Kozo Kaiseki no Tameno Seitaimaku Naizaisei PR772 Phage Ryushi no Saikoseikei no Kakuritsu", pages: 711
ABRESCIA, N. G. A. ET AL.: "Insights into assembly from structural analysis of bacteriophage PRD1", NATURE, vol. 432, 2004, pages 68 - 74
Attorney, Agent or Firm:
OZAWA, Nobuhiko (Ginza Satomura Building 5F 27-7 Ginza 1-chome, Chuo-k, Tokyo 61, JP)
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