Title:
BIOLOGICAL SAMPLE MICROCHIP, COVER, BIOLOGICAL SAMPLE SEALING KIT AND METHOD
Document Type and Number:
WIPO Patent Application WO/2019/225633
Kind Code:
A1
Abstract:
Provided is a biological sample microchip suitable for being locally irradiated with a microbeam or for observing cells, tissues, etc. in a state where a biological sample is cultured or sealed therein. In the biological sample microchip, at least one recessed section for culturing or sealing a biological sample is formed in a surface thereof, and the overall thickness of the microchip is formed to be 800 µm or less. Further, in the biological sample microchip, hydrophilicity is imparted to the surface of the microchip in which the recessed section for culturing or sealing the biological sample is formed.
Inventors:
SUZUKI MICHIYO (JP)
SAKASHITA TETSUYA (JP)
FUNAYAMA TOMOO (JP)
HIRATSUKA HAJIME (JP)
SAKASHITA TETSUYA (JP)
FUNAYAMA TOMOO (JP)
HIRATSUKA HAJIME (JP)
Application Number:
PCT/JP2019/020219
Publication Date:
November 28, 2019
Filing Date:
May 22, 2019
Export Citation:
Assignee:
NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECH (JP)
BIOCOSM INC (JP)
BIOCOSM INC (JP)
International Classes:
C12M1/00; C12M1/34; C12M3/00
Domestic Patent References:
| WO2015034011A1 | 2015-03-12 | |||
| WO2018061795A1 | 2018-04-05 |
Foreign References:
| JP2007089566A | 2007-04-12 | |||
| JP2005000047A | 2005-01-06 |
Other References:
SUGIMOTO, T. ET AL.: "Cell cycle arrest and apoptosis in Caenorhabditis elegans germline cells following heavy-ion microbeam irradiation", INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, vol. 82, no. 1, 2006, pages 31, 38
SUZUKI, M. ET AL.: "Region-specific irradiation system with heavy-ion microbeam for active individuals of Caenorhabditis elegans", JOURNAL OF RADIATION RESEARCH, vol. 58, no. 6, 2017, pages 881 - 886, XP055656210
SUZUKI, M. ET AL.: "Region-specific irradiation system with heavy-ion microbeam for active individuals of Caenorhabditis elegans", JOURNAL OF RADIATION RESEARCH, vol. 58, no. 6, 2017, pages 881 - 886, XP055656210
Attorney, Agent or Firm:
TAKAGAKI Yasushi (JP)
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