Title:
BIOMARKER COMPOSITION FOR DIAGNOSIS OF SKIN BARRIER FUNCTION
Document Type and Number:
WIPO Patent Application WO/2018/062683
Kind Code:
A1
Abstract:
Described are a biomarker composition for diagnosis of skin barrier function, the composition testing the expression level of at least one gene of OR6M1 and OR6V1 in a specimen, a kit, and a diagnostic method using the same. A unit for objective diagnosis of skin barrier function may be provided.
Inventors:
SON EUI DONG (KR)
JEON BYEONG BAE (KR)
KIM JI HYUN (KR)
KIM KYU HAN (KR)
PARK SUN YOUNG (KR)
KIM HYOUNG JUNE (KR)
CHOI MIN SIK (KR)
CHO EUN-GYUNG (KR)
LEE TAE RYONG (KR)
JEON BYEONG BAE (KR)
KIM JI HYUN (KR)
KIM KYU HAN (KR)
PARK SUN YOUNG (KR)
KIM HYOUNG JUNE (KR)
CHOI MIN SIK (KR)
CHO EUN-GYUNG (KR)
LEE TAE RYONG (KR)
Application Number:
PCT/KR2017/008955
Publication Date:
April 05, 2018
Filing Date:
August 17, 2017
Export Citation:
Assignee:
AMOREPACIFIC CORP (KR)
International Classes:
C12Q1/68; G01N33/577; G01N33/68
Foreign References:
| US20100255478A1 | 2010-10-07 | |||
| KR20140089505A | 2014-07-15 |
Other References:
BUSSE, DANIELA ET AL.: "A Synthetic Sandalwood Odorant Induces Wound-healing Processes in Human Keratinocytes via the Olfactory Receptor OR2 AT 4", JOURNAL OF INVESTIGATIVE DENNATOLOGY, vol. 134, 7 August 2014 (2014-08-07), pages 2823 - 2832, XP055534614, DOI: doi:10.1038/jid.2014.273
DENDA, MITSUHIRO: "Newly Discovered Olfactory Receptors in Epidermal Keratinocytes Are Associated with Proliferation, Migration, and Re-epitheliazation of Keratinocytes", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 134, no. 11, 2014, pages 2677 - 2679, XP055584109
ABAFFY, TATJANA: "Human Olfactory Receptors Expression and Their Role in Non-olfactory Tissues-a mini-review", JOURNAL OF PHARMACOGENOMICS & PHARMACOPROTEOMICS, vol. 6, no. 4, 6 October 2015 (2015-10-06), pages 1 - 7, XP055584111
J ALLERGY CLIN IMMUNOL., vol. 127, no. 3, March 2011 (2011-03-01), pages 773 - 86
See also references of EP 3521449A4
DENDA, MITSUHIRO: "Newly Discovered Olfactory Receptors in Epidermal Keratinocytes Are Associated with Proliferation, Migration, and Re-epitheliazation of Keratinocytes", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 134, no. 11, 2014, pages 2677 - 2679, XP055584109
ABAFFY, TATJANA: "Human Olfactory Receptors Expression and Their Role in Non-olfactory Tissues-a mini-review", JOURNAL OF PHARMACOGENOMICS & PHARMACOPROTEOMICS, vol. 6, no. 4, 6 October 2015 (2015-10-06), pages 1 - 7, XP055584111
J ALLERGY CLIN IMMUNOL., vol. 127, no. 3, March 2011 (2011-03-01), pages 773 - 86
See also references of EP 3521449A4
Attorney, Agent or Firm:
KIM, Sun-young (KR)
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