Title:
BIOMARKER FOR DIAGNOSING AGE-RELATED MACULAR DEGENERATION OR DIABETIC RETINOPATHY AND METHOD FOR DIAGNOSIS USING SAME
Document Type and Number:
WIPO Patent Application WO/2017/086703
Kind Code:
A1
Abstract:
A composition, a kit or a method for providing necessary information for diagnosing age-related macular degeneration or diabetic retinopathy according to an aspect of the invention, which is a novel immunological diagnostic means using the plasma of a patient, not only exhibits excellent sensitivity but also enables easy analysis of the plasma without the use of a biopsy, and thus can be useful for early diagnosis of age-related macular degeneration or diabetic retinopathy.
Inventors:
LEE CHEOL JU (KR)
AHN HEE SUNG (KR)
PARK SEONG JUN (KR)
HAN KI CHEOL (KR)
LEE JI EUN (KR)
KIM CHONG HYUN (KR)
WOO SE JOON (KR)
PARK KYU HUNG (KR)
HONG HYE KYOUNG (KR)
AHN HEE SUNG (KR)
PARK SEONG JUN (KR)
HAN KI CHEOL (KR)
LEE JI EUN (KR)
KIM CHONG HYUN (KR)
WOO SE JOON (KR)
PARK KYU HUNG (KR)
HONG HYE KYOUNG (KR)
Application Number:
PCT/KR2016/013235
Publication Date:
May 26, 2017
Filing Date:
November 16, 2016
Export Citation:
Assignee:
RETI MARK CO LTD (KR)
SEOUL NAT UNIV BUNDANG HOSPITAL (KR)
SEOUL NAT UNIV BUNDANG HOSPITAL (KR)
International Classes:
C12Q1/68; C07K14/575; C12N15/115; G01N33/532
Foreign References:
| KR20140117772A | 2014-10-08 |
Other References:
KIM: "Identification of vinculin as a potential plasma marker for age-related macular degeneration", INVESTIGATIVE OPHTHALMOLOGY AND VISUAL SCIENCE, vol. 55, no. 11, 2014, pages 7166 - 7176, XP055598335, DOI: 10.1167/iovs.14-15168
WANG: "Intraocular expression of thymosin beta 4 in proliferative diabetic retinopathy", ACTA OPHTHALMOLOGICA, vol. 89, no. 5, 2011, pages e396 - e403, XP055598336, DOI: 10.1111/j.1755-3768.2011.02114.x
CHEN, X. ET AL.: "Diabetes mellitus and risk of age-related macular degeneration: a systematic review and meta-analysis", PLOS ONE, vol. 9, no. 9, September 2014 (2014-09-01), pages 1 - 12, XP055598338, DOI: 10.1371/journal.pone.0108196
GIBSON: "Diabetic retinopathy and age-related macular degeneration in the US", AMERICAN JOURNAL OF PREVENTIVE MEDICINE, vol. 43, no. 1, 2012, pages 48 - 54, XP028493116, DOI: doi:10.1016/j.amepre.2012.02.028
WANG: "Intraocular expression of thymosin beta 4 in proliferative diabetic retinopathy", ACTA OPHTHALMOLOGICA, vol. 89, no. 5, 2011, pages e396 - e403, XP055598336, DOI: 10.1111/j.1755-3768.2011.02114.x
CHEN, X. ET AL.: "Diabetes mellitus and risk of age-related macular degeneration: a systematic review and meta-analysis", PLOS ONE, vol. 9, no. 9, September 2014 (2014-09-01), pages 1 - 12, XP055598338, DOI: 10.1371/journal.pone.0108196
GIBSON: "Diabetic retinopathy and age-related macular degeneration in the US", AMERICAN JOURNAL OF PREVENTIVE MEDICINE, vol. 43, no. 1, 2012, pages 48 - 54, XP028493116, DOI: doi:10.1016/j.amepre.2012.02.028
Attorney, Agent or Firm:
ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)
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