Title:
BIOMARKER FOR PREDICTING CANCER PROGNOSIS
Document Type and Number:
WIPO Patent Application WO/2022/215991
Kind Code:
A1
Abstract:
The present invention relates to a composition for predicting the prognosis of a cancer patient, comprising a preparation for measuring the expression level of NFX1 genes or proteins thereof and/or MFN2 genes or proteins thereof.
Inventors:
CHEONG JAE-HO (KR)
PARK KI CHEONG (KR)
KIM JUNGMIN (KR)
CHOI HAE JI (KR)
PARK KI CHEONG (KR)
KIM JUNGMIN (KR)
CHOI HAE JI (KR)
Application Number:
PCT/KR2022/004834
Publication Date:
October 13, 2022
Filing Date:
April 05, 2022
Export Citation:
Assignee:
UNIV YONSEI IACF (KR)
International Classes:
C12Q1/6886; G01N33/574
Domestic Patent References:
| WO2013147330A1 | 2013-10-03 |
Foreign References:
| US20160312309A1 | 2016-10-27 |
Other References:
FANG CHIA-LANG, SUN DING-PING, CHEN HAN-KUN, LIN CHIH-CHAN, HUNG SHIH-TING, UEN YIH-HUEI, LIN KAI-YUAN: "Overexpression of Mitochondrial GTPase MFN2 Represents a Negative Prognostic Marker in Human Gastric Cancer and Its Inhibition Exerts Anti-Cancer Effects", JOURNAL OF CANCER, IVYSPRING INTERNATIONAL PUBLISHER, AU, vol. 8, no. 7, 1 January 2017 (2017-01-01), AU , pages 1153 - 1161, XP055976873, ISSN: 1837-9664, DOI: 10.7150/jca.17986
DECKER CARL W., GARCIA JEROME, GATCHALIAN KRISTELLE, ARCENEAUX DERONISHA, CHOI CLARICE, CAVE SI, HAN DERICK, HERNANDEZ JENIFFER B.: "Mitofusin-2 mediates doxorubicin sensitivity and acute resistance in Jurkat leukemia cells", BIOCHEMISTRY AND BIOPHYSICS REPORTS, ELSEVIER, vol. 24, 1 December 2020 (2020-12-01), pages 100824, XP055976876, ISSN: 2405-5808, DOI: 10.1016/j.bbrep.2020.100824
KIM JUNGMIN, CHEONG JAE-HO: "Role of Mitochondria-Cytoskeleton Interactions in the Regulation of Mitochondrial Structure and Function in Cancer Stem Cells", CELLS, vol. 9, no. 7, 1 January 2020 (2020-01-01), pages 1691, XP055976879, DOI: 10.3390/cells9071691
DECKER CARL W., GARCIA JEROME, GATCHALIAN KRISTELLE, ARCENEAUX DERONISHA, CHOI CLARICE, CAVE SI, HAN DERICK, HERNANDEZ JENIFFER B.: "Mitofusin-2 mediates doxorubicin sensitivity and acute resistance in Jurkat leukemia cells", BIOCHEMISTRY AND BIOPHYSICS REPORTS, ELSEVIER, vol. 24, 1 December 2020 (2020-12-01), pages 100824, XP055976876, ISSN: 2405-5808, DOI: 10.1016/j.bbrep.2020.100824
KIM JUNGMIN, CHEONG JAE-HO: "Role of Mitochondria-Cytoskeleton Interactions in the Regulation of Mitochondrial Structure and Function in Cancer Stem Cells", CELLS, vol. 9, no. 7, 1 January 2020 (2020-01-01), pages 1691, XP055976879, DOI: 10.3390/cells9071691
Attorney, Agent or Firm:
PADO IP LAW PLLC (KR)
Download PDF: