Title:
BIOMARKER FOR PROGNOSIS OF STOMACH CANCER AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/145532
Kind Code:
A1
Abstract:
The present invention relates to a method for providing information for easy and simple prognosis of stomach cancer by determining better prognosis of stomach cancer in a subject, compared to a control, when the level of enhancer of rudimentary homolog (ERH) mRNA or protein in a sample isolated from the subject with stomach cancer is measured to be higher than that in the control.
Inventors:
PARK JI HO (KR)
JEONG SANG HO (KR)
JEONG SANG HO (KR)
Application Number:
PCT/KR2020/019360
Publication Date:
July 07, 2022
Filing Date:
December 30, 2020
Export Citation:
Assignee:
GYEONGSANG NATIONAL UNIV HOSPITAL (KR)
International Classes:
G01N33/574; A61K48/00; A61P35/04; C12N15/113; C12Q1/6886
Foreign References:
| KR20190114298A | 2019-10-10 |
Other References:
PARK JI-HO, PARK MIYEONG, PARK SUN YI, LEE YOUNG-JOON, HONG SOON-CHAN, JUNG EUN-JUNG, JU YOUNG-TAE, JEONG CHI-YOUNG, KIM JU-YEON, : "ERH overexpression is associated with decreased cell migration and invasion and a good prognosis in gastric cancer", TRANSLATIONAL CANCER RESEARCH, vol. 9, no. 9, 1 September 2020 (2020-09-01), pages 5281 - 5291, XP055947697, ISSN: 2218-676X, DOI: 10.21037/tcr-20-1498
JEONG SANG-HO; KIM ROCK BUM; PARK SUN YI; PARK JIHO; JUNG EUN-JUNG; JU YOUNG-TAE; JEONG CHI-YOUNG; PARK MIYEONG; KO GYUNG HYUCK; S: "Nomogram for predicting gastric cancer recurrence using biomarker gene expression", EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, vol. 46, no. 1, 21 September 2019 (2019-09-21), GB , pages 195 - 201, XP085983466, ISSN: 0748-7983, DOI: 10.1016/j.ejso.2019.09.143
BALIC JESSE J., GARAMA DANIEL J., SAAD MOHAMED I., YU LIANG, WEST ALISON C., WEST ALICE J., LIVIS THALEIA, BHATHAL PRITHI S., GOUG: "Serine-Phosphorylated STAT3 Promotes Tumorigenesis via Modulation of RNA Polymerase Transcriptional Activity", CANCER RESEARCH, vol. 79, no. 20, 1 January 2019 (2019-01-01), US , pages 5272 - 5287, XP055947707, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-19-0974
ZAFRAKAS MENELAOS, LOSEN INGE, KNÜCHEL RUTH, DAHL EDGAR: "Enhancer of the rudimentary gene homologue (ERH) expression pattern in sporadic human breast cancer and normal breast tissue", BMC CANCER, vol. 8, no. 1, 1 December 2008 (2008-12-01), pages 1 - 8, XP055947708, DOI: 10.1186/1471-2407-8-145
JEONG SANG-HO; KIM ROCK BUM; PARK SUN YI; PARK JIHO; JUNG EUN-JUNG; JU YOUNG-TAE; JEONG CHI-YOUNG; PARK MIYEONG; KO GYUNG HYUCK; S: "Nomogram for predicting gastric cancer recurrence using biomarker gene expression", EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, vol. 46, no. 1, 21 September 2019 (2019-09-21), GB , pages 195 - 201, XP085983466, ISSN: 0748-7983, DOI: 10.1016/j.ejso.2019.09.143
BALIC JESSE J., GARAMA DANIEL J., SAAD MOHAMED I., YU LIANG, WEST ALISON C., WEST ALICE J., LIVIS THALEIA, BHATHAL PRITHI S., GOUG: "Serine-Phosphorylated STAT3 Promotes Tumorigenesis via Modulation of RNA Polymerase Transcriptional Activity", CANCER RESEARCH, vol. 79, no. 20, 1 January 2019 (2019-01-01), US , pages 5272 - 5287, XP055947707, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-19-0974
ZAFRAKAS MENELAOS, LOSEN INGE, KNÜCHEL RUTH, DAHL EDGAR: "Enhancer of the rudimentary gene homologue (ERH) expression pattern in sporadic human breast cancer and normal breast tissue", BMC CANCER, vol. 8, no. 1, 1 December 2008 (2008-12-01), pages 1 - 8, XP055947708, DOI: 10.1186/1471-2407-8-145
Attorney, Agent or Firm:
LEECHAE INTELLECTUAL PROPERTY (KR)
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