Title:
BIOMARKERS FOR BREAST CANCER AND METHODS OF USING SAME
Document Type and Number:
WIPO Patent Application WO/2014/071218
Kind Code:
A3
Abstract:
Provided are methods of treating breast cancer. Further provided are methods and kits for assessing the likelihood that breast cancer in a subject will metastasize or has metastasized. Further provided are methods and kits for determining whether a subject having breast cancer would benefit from treatment with at least one of a RON inhibitor and a PI3K kinase inhibitor. Further provided are methods of monitoring a molecular response of a subject to treatment of breast cancer with at least one of a RON inhibitor and a PI3K inhibitor.
Inventors:
CUNHA STEPHANIE (US)
WELM ALANA LEE (US)
WELM ALANA LEE (US)
Application Number:
PCT/US2013/068117
Publication Date:
July 16, 2015
Filing Date:
November 01, 2013
Export Citation:
Assignee:
UNIV UTAH RES FOUND (US)
International Classes:
C12Q1/68
Domestic Patent References:
| WO2011088149A2 | 2011-07-21 | |||
| WO2012112645A1 | 2012-08-23 |
Foreign References:
| US20090170084A1 | 2009-07-02 | |||
| US20110145176A1 | 2011-06-16 | |||
| US20100131432A1 | 2010-05-27 |
Other References:
PRINZ ET AL.: "Elimination of breast tumor-associated chondroitin sulfate promotes metastasis.", GENETICS AND MOLECULAR RESEARCH, vol. 10, no. ISSUE, 8 December 2011 (2011-12-08), pages 3901 - 3913
LIU ET AL.: "Short-Form Ron Promotes Spontaneous Breast Cancer Metastasis through Interaction with Phosphoinositide 3-Kinase'.", GENES & CANCER., vol. 2, no. 7, July 2011 (2011-07-01), pages 753 - 762
LIU ET AL.: "Short-Form Ron Promotes Spontaneous Breast Cancer Metastasis through Interaction with Phosphoinositide 3-Kinase'.", GENES & CANCER., vol. 2, no. 7, July 2011 (2011-07-01), pages 753 - 762
Attorney, Agent or Firm:
LANGER, Michael, R. (100 East Wisconsin Avenue Suite 330, Milwaukee WI, US)
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