BIOMARKERS AND METHODS FOR PROGRESSION PREDICTION FOR CHRONIC KIDNEY DISEASE

WIPO Patent Application WO/2015/063248

A3

Subject of the present invention are biomarkers and methods for the identification of an increased risk of the progression of chronic kidney disease (CKD), or for monitoring chronic kidney disease therapy, comprising the detecting the level of one or more of NTpro BNP, EGF, Apo H, GDF-15, and albumin-to-creatinine ratio.

BOBADILLA MARIA (FR)
BADI LAURA (CH)
DUCHATEAU-NGUYEN GUILLEMETTE (FR)
ESSIOUX LAURENT (FR)
LANGEN HANNO (DE)
MAGNONE MARIA CHIARA (CH)
SCHINDLER THOMAS (DE)
THIER MARTINA (CH)
FORMENTINI IVAN (CH)
DURAN PACHECO GONZALO CHRISTIAN (CH)
SOLIER CORINNE (FR)
KRETZLER MATTHIAS (US)
NAIR VIJI (US)
JU WENJU (US)

PCT/EP2014/073413

August 13, 2015

October 31, 2014

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HOFFMANN LA ROCHE (US)
HOFFMANN LA ROCHE (US)
UNIV MICHIGAN (US)

G01N33/68

WO2010048670A1

2010-05-06

EP2336784A1	2011-06-22
EP2388594A1	2011-11-23

BORJA QUIROGA ET AL: "Inflammatory Biomarkers in Chronic Kidney Disease: A Review", RECENT PATENTS ON BIOMARKERS, vol. 2, no. 2, 1 May 2012 (2012-05-01), pages 131 - 138, XP055164985, ISSN: 2210-3104, DOI: 10.2174/2210309011202020131
DATABASE OMIM [online] "Growth/differentiation factor 15; GDF15", XP002735116, retrieved from NCBI Database accession no. 605312

BRODBECK, Michel (Basel, CH)

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