Title:
BIOMIMETIC TISSUE SCAFFOLD AND METHODS OF MAKING AND USING SAME
Document Type and Number:
WIPO Patent Application WO/2011/163551
Kind Code:
A3
Abstract:
Three-dimensional biomimetic tissue scaffolds, as well as methods of manufacture of these scaffolds. The method is fully customizable to create a biomimetic tissue scaffold with shapes, densities, and geometries similar or identical to the tissue it imitates. For example, physiologically realistic collagen/PEG villi created using the method are designed to have a high-aspect ratio and curvature similar to villi found in the human small intestine. Accordingly, the biomimetic tissue scaffolds serve as an improved in vitro model for a wide variety of physiological research, as well as pharmacological testing and drug, compound, and/or metabolite uptake by cells growing on the scaffold, among many other uses.
Inventors:
MARCH JOHN C (US)
YU JIAJIE (US)
SUNG JONG HWAN (US)
YU JIAJIE (US)
SUNG JONG HWAN (US)
Application Number:
PCT/US2011/041746
Publication Date:
April 12, 2012
Filing Date:
June 24, 2011
Export Citation:
Assignee:
UNIV CORNELL (US)
MARCH JOHN C (US)
YU JIAJIE (US)
SUNG JONG HWAN (US)
MARCH JOHN C (US)
YU JIAJIE (US)
SUNG JONG HWAN (US)
International Classes:
B29C39/20; A61F2/02; A61L27/14
Foreign References:
| US6479072B1 | 2002-11-12 | |||
| US20090061152A1 | 2009-03-05 | |||
| US20070036844A1 | 2007-02-15 |
Other References:
LEE ET AL.: "Scaffold fabrication by indirect three-dimensional printing", BIOMATERIALS., vol. 26, 2005, pages 4281 - 4289
Attorney, Agent or Firm:
GREENER, William (Suite 102Bond, Schoeneck & King, PLL, Ithaca New York, US)
Download PDF:
Previous Patent: METHOD AND APPARATUS FOR RELIABLY LASER MARKING ARTICLES
Next Patent: EFFICIENT PAIRING OF NETWORKED DEVICES
Next Patent: EFFICIENT PAIRING OF NETWORKED DEVICES