Title:
BIOMOLECULAR GROUP RELATED TO CELL ANTI-AGING
Document Type and Number:
WIPO Patent Application WO/2015/030149
Kind Code:
A1
Abstract:
The purpose of the present invention is to make clear a method for producing a novel Muse cytoid cell and a method for extending the lifespan of a cell population. A method for producing a Muse cytoid cell comprising a step for blocking the expression or function of ELAVL2, TEAD1, and GATAD2B is used. In the step, the expression or function of ELAVL2, TEAD1, and GATAD2B may be blocked by siRNA or shRNA.
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Inventors:
MIURA NORIMASA (JP)
Application Number:
PCT/JP2014/072661
Publication Date:
March 05, 2015
Filing Date:
August 28, 2014
Export Citation:
Assignee:
NAT UNIV CORP TOTTORI UNIV (JP)
International Classes:
C12N5/10; A61K35/12; A61K45/00; A61L27/00; A61P43/00; C12N15/113
Domestic Patent References:
| WO2014097875A1 | 2014-06-26 | |||
| WO2011007900A1 | 2011-01-20 | |||
| WO2012008302A1 | 2012-01-19 | |||
| WO2009045443A2 | 2009-04-09 | |||
| WO2011146879A2 | 2011-11-24 | |||
| WO2007069666A1 | 2007-06-21 | |||
| WO2009075119A1 | 2009-06-18 | |||
| WO2012008301A1 | 2012-01-19 | |||
| WO2012008302A1 | 2012-01-19 |
Foreign References:
| JP2013528368A | 2013-07-11 | |||
| JP2010504350A | 2010-02-12 | |||
| JP2012085645A | 2012-05-10 | |||
| JP5185443B2 | 2013-04-17 |
Other References:
TSUNO S. ET AL.: "Hsa-miR-520d induces hepatoma cells to form normal liver tissues via a stemness-mediated process.", SCIENTIFIC REPORTS, vol. 4, no. 3852, 24 January 2014 (2014-01-24), pages 1 - 14, XP055152771
BRADLEY A. ET AL.: "Embryonic stem cells: proliferation and differentiation.", CURRENT OPINION IN CELL, vol. 2, no. 6, 1990, pages 1013 - 1017, XP025481514
YASUSHI HASEGAWA: "Biyo Hifuka no Frontline - Hifu no Kansaibo Kenkyu o Do Biyo Bun'ya e Ikasu ka", VISUAL DERMATOLOGY, vol. 12, no. 6, 25 May 2013 (2013-05-25), pages 592 - 597, XP008182984
KNIGHT JF. ET AL.: "TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer.", BRITISH JOURNAL OF CANCER, vol. 99, 2008, pages 1849 - 1858, XP002581829
WISZNIAK S.E. ET AL.: "HuB (elavl2) mRNA Is Restricted to the Germ Cells by Post- Transcriptional Mechanisms including Stabilisation of the Message by DAZL.", PLOS ONE, vol. 6, no. 6, 2011, pages E20773, 1 - 8, XP055322458
HONG ET AL.: "Suppression of induced pluripotent stem cell generation by the p53-p21 pathway", NATURE, vol. 460, no. 7259, 9 August 2009 (2009-08-09), pages 1132 - 5
CLACKSON ET AL., NATURE, vol. 352, no. 6336, 15 August 1991 (1991-08-15), pages 624 - 628
NAITO ET AL., BMC BIOINFORMATICS, vol. 10, 30 November 2009 (2009-11-30), pages 392
BERGE ET AL., J. PHARM. SCI., vol. 66, 1977, pages 1 - 19
J. HONIG ET AL., THE VAN NOSTRAND CHEMIST'S DICTIONARY, 1953, pages 650
AUSUBEL ET AL.: "Current Protocols in Molecular Biology", 1995, WILEY INTERSCIENCE PUBLISHERS
See also references of EP 3040414A4
BRADLEY A. ET AL.: "Embryonic stem cells: proliferation and differentiation.", CURRENT OPINION IN CELL, vol. 2, no. 6, 1990, pages 1013 - 1017, XP025481514
YASUSHI HASEGAWA: "Biyo Hifuka no Frontline - Hifu no Kansaibo Kenkyu o Do Biyo Bun'ya e Ikasu ka", VISUAL DERMATOLOGY, vol. 12, no. 6, 25 May 2013 (2013-05-25), pages 592 - 597, XP008182984
KNIGHT JF. ET AL.: "TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer.", BRITISH JOURNAL OF CANCER, vol. 99, 2008, pages 1849 - 1858, XP002581829
WISZNIAK S.E. ET AL.: "HuB (elavl2) mRNA Is Restricted to the Germ Cells by Post- Transcriptional Mechanisms including Stabilisation of the Message by DAZL.", PLOS ONE, vol. 6, no. 6, 2011, pages E20773, 1 - 8, XP055322458
HONG ET AL.: "Suppression of induced pluripotent stem cell generation by the p53-p21 pathway", NATURE, vol. 460, no. 7259, 9 August 2009 (2009-08-09), pages 1132 - 5
CLACKSON ET AL., NATURE, vol. 352, no. 6336, 15 August 1991 (1991-08-15), pages 624 - 628
NAITO ET AL., BMC BIOINFORMATICS, vol. 10, 30 November 2009 (2009-11-30), pages 392
BERGE ET AL., J. PHARM. SCI., vol. 66, 1977, pages 1 - 19
J. HONIG ET AL., THE VAN NOSTRAND CHEMIST'S DICTIONARY, 1953, pages 650
AUSUBEL ET AL.: "Current Protocols in Molecular Biology", 1995, WILEY INTERSCIENCE PUBLISHERS
See also references of EP 3040414A4
Attorney, Agent or Firm:
SK INTELLECTUAL PROPERTY LAW FIRM et al. (JP)
SK patent business corporation (JP)
SK patent business corporation (JP)
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