Title:
BIOSENSOR, DETECTION METHOD, AND DETECTION DEVICE
Document Type and Number:
WIPO Patent Application WO/2022/196179
Kind Code:
A1
Abstract:
A biosensor 1 is a biosensor of a field effect transistor type, which is equipped with an insulating substrate 10 and a measurement sensor S1 and a reference sensor S2 both provided on the insulating substrate 10. On the measurement sensor S1, probe molecules 16 are provided. Each of the probe molecules 16 has a first base moiety 14 that is provided on the measurement sensor S1 and a recognition moiety 15 of which one end is bound to the first base moiety 14 and the other end constitutes a tip part of the probe molecule 16. On the reference sensor S2, a second base moiety 24 is provided, which has the same structure as that of the first base moiety 14 of each of the probe molecules 16 provided on the measurement sensor S1. At a tip part of the second base moiety 24, the recognition moiety 15 of each of the probe molecules 16 provided on the measurement sensor S1 is not present.
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Inventors:
SUZUKI YASUO (JP)
USHIBA SHOTA (JP)
MIYAKAWA NARUTO (JP)
ONO TAKAO (JP)
MATSUMOTO KAZUHIKO (JP)
USHIBA SHOTA (JP)
MIYAKAWA NARUTO (JP)
ONO TAKAO (JP)
MATSUMOTO KAZUHIKO (JP)
Application Number:
PCT/JP2022/004686
Publication Date:
September 22, 2022
Filing Date:
February 07, 2022
Export Citation:
Assignee:
MURATA MANUFACTURING CO (JP)
UNIV OSAKA (JP)
SUZUKI YASUO (JP)
UNIV OSAKA (JP)
SUZUKI YASUO (JP)
International Classes:
C07K17/00; C12M1/34; C12Q1/04; G01N27/26; G01N27/414
Foreign References:
| JP2017121205A | 2017-07-13 | |||
| JP2013152211A | 2013-08-08 | |||
| JP2019095204A | 2019-06-20 | |||
| JP2014518567A | 2014-07-31 |
Other References:
YAMAMOTO K., ONO T, MIYAKAWA N, KANAI Y, KOYAMA T, TANIOKU M, USHIBA S, SHINAGAWA A, INOUE K, WATANABE Y, NAKAKITA S, KAWAHARA T, : "Detection of Human Influenza Virus using Graphene-FET Array", EXTENDED ABSTRACTS OF THE 68TH JSAP SPRING MEETING, vol. 68, no. 16p-Z22-7, 26 February 2021 (2021-02-26), XP055967984
KAWATA TAKUYA, ONO TAKAO, KANAI YASUSHI, OHNO YASUHIDE, MAEHASHI KENZO, INOUE KOICHI, MATSUMOTO KAZUHIKO: "Improved sensitivity of a graphene FET biosensor using porphyrin linkers", JAPANESE JOURNAL OF APPLIED PHYSICS, JAPAN SOCIETY OF APPLIED PHYSICS, JP, vol. 57, no. 6, 1 June 2018 (2018-06-01), JP , pages 065103, XP055967989, ISSN: 0021-4922, DOI: 10.7567/JJAP.57.065103
SHOTA USHIBA, NARUTO MIYAKAWA, TSUYOSHI OKINO, AYUMI SHINAGAWA, YUKA OKA, MASAHIKO KIMURA, TAKAO ONO, YASUSHI KANAI, KOICHI INOUE,: "Biosensing Platforms Based on Graphene Field Effect Transistors", VACUUM AND SURFACE SCIENCE, THE JAPAN SOCIETY OF VACUUM AND SURFACE SCIENCE, vol. 63, no. 7, 1 January 2020 (2020-01-01), pages 358 - 363, XP009539737, ISSN: 2433-5835, DOI: 10.1380/vss.63.358
KAWATA TAKUYA, ONO TAKAO, KANAI YASUSHI, OHNO YASUHIDE, MAEHASHI KENZO, INOUE KOICHI, MATSUMOTO KAZUHIKO: "Improved sensitivity of a graphene FET biosensor using porphyrin linkers", JAPANESE JOURNAL OF APPLIED PHYSICS, JAPAN SOCIETY OF APPLIED PHYSICS, JP, vol. 57, no. 6, 1 June 2018 (2018-06-01), JP , pages 065103, XP055967989, ISSN: 0021-4922, DOI: 10.7567/JJAP.57.065103
SHOTA USHIBA, NARUTO MIYAKAWA, TSUYOSHI OKINO, AYUMI SHINAGAWA, YUKA OKA, MASAHIKO KIMURA, TAKAO ONO, YASUSHI KANAI, KOICHI INOUE,: "Biosensing Platforms Based on Graphene Field Effect Transistors", VACUUM AND SURFACE SCIENCE, THE JAPAN SOCIETY OF VACUUM AND SURFACE SCIENCE, vol. 63, no. 7, 1 January 2020 (2020-01-01), pages 358 - 363, XP009539737, ISSN: 2433-5835, DOI: 10.1380/vss.63.358
Attorney, Agent or Firm:
WISEPLUS IP FIRM (JP)
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