Title:
BIOSYNTHETIC GENE CLUSTER FOR CHEJUENOLIDE OF MARINE MICROORGANISM HAHELLA CHEJUENSIS
Document Type and Number:
WIPO Patent Application WO/2013/125777
Kind Code:
A1
Abstract:
The present invention relates to a biosynthetic gene cluster for a chejuenolide of the marine microorganism Hahella chejuensis, and to the function of an enzyme involving the biosynthetic pathway of a chejuenolide coded by the genes. Since the present invention can be applied to the development of a novel material as a mechanism for biosynthesis by combining of biosynthetic genes for chejuenolide, the present invention can suggest a new direction in the study of polyketide antibiotics, and is thus very useful.
Inventors:
KIM BEOM SEOK (KR)
OH HYUNCHEOL (KR)
NG BEE-GEK (MY)
HAN JAE-WOO (KR)
OH HYUNCHEOL (KR)
NG BEE-GEK (MY)
HAN JAE-WOO (KR)
Application Number:
PCT/KR2012/010879
Publication Date:
August 29, 2013
Filing Date:
December 14, 2012
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
C12N15/31; C07D309/38; C12N1/21; C12N15/63
Other References:
DATABASE GENBANK 24 January 2012 (2012-01-24), accession no. P_434661.1
DATABASE GENBANK 24 January 2012 (2012-01-24), accession no. P_434646.1
DATABASE GENBANK 24 January 2012 (2012-01-24), accession no. P_434654.1
DATABASE GENBANK 24 January 2012 (2012-01-24), accession no. P_434309.1
DATABASE GENBANK 24 January 2012 (2012-01-24), accession no. P_434311.1
DATABASE GENBANK 6 October 2010 (2010-10-06), accession no. P000155.1
CHOI, Y. H. ET AL.: "Chejuenolides A and B, new macrocyclic tetraenes from the marine bacterium Hahella chejuensis", TETRAHEDRON LETTERS, vol. 49, 2008, pages 7128 - 7131, XP025587380
SEO, C. ET AL.: "Chejuenolide C: A New Macrocyclic Metabolite from the Marine Bacterium Hahella chejuensis", BULL. KOREAN CHEM. SOC., vol. 30, no. 5, 2009, pages 1181 - 1183, XP003032411
DATABASE GENBANK 24 January 2012 (2012-01-24), accession no. P_434646.1
DATABASE GENBANK 24 January 2012 (2012-01-24), accession no. P_434654.1
DATABASE GENBANK 24 January 2012 (2012-01-24), accession no. P_434309.1
DATABASE GENBANK 24 January 2012 (2012-01-24), accession no. P_434311.1
DATABASE GENBANK 6 October 2010 (2010-10-06), accession no. P000155.1
CHOI, Y. H. ET AL.: "Chejuenolides A and B, new macrocyclic tetraenes from the marine bacterium Hahella chejuensis", TETRAHEDRON LETTERS, vol. 49, 2008, pages 7128 - 7131, XP025587380
SEO, C. ET AL.: "Chejuenolide C: A New Macrocyclic Metabolite from the Marine Bacterium Hahella chejuensis", BULL. KOREAN CHEM. SOC., vol. 30, no. 5, 2009, pages 1181 - 1183, XP003032411
Attorney, Agent or Firm:
KIM, SEON AE (KR)
김선애 (KR)
김선애 (KR)
Download PDF:
Claims: