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Title:
BIPHENYL AMIDES WITH MODIFIED ETHER GROUPS AS HSP90 INHIBITORS AND HSP70 INDUCERS
Document Type and Number:
WIPO Patent Application WO/2015/200514
Kind Code:
A3
Abstract:
Provided herein are compounds of the formulas: (I) wherein: n, X2, R3, R3', R4, R4', R5, R5', R6, and R6' are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases, including diabetic peripheral neuropathy or cancer.

Inventors:
BLAGG, Brian, S.J. (4705 Woodland Drive, Lawrence, KS, 66044, US)
DOBROWSKY, Rick, T. (12502 S. Alden Ct, Olathe, KS, 66062, US)
ANYIKA, Mercy (3100 W 22nd St. Apt. E6, Lawrence, KS, 66047, US)
Application Number:
US2015/037478
Publication Date:
February 25, 2016
Filing Date:
June 24, 2015
Export Citation:
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Assignee:
THE UNIVERSITY OF KANSAS (245 Strong Hall, 1450 Jayhawk BoulevardLawrence, KS, 66045, US)
International Classes:
C07H15/203; A61P25/00; C07C233/05; C07D307/20; C07D309/10; C07D311/08
Domestic Patent References:
WO2013119985A12013-08-15
Attorney, Agent or Firm:
LONG, S., Reid (Parker Highlander PLLC, 1120 S. Capital of Texas HighwayBuilding One, Suite 20, Austin TX, 78746, US)
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