Title:
BIPYRIDYL DERIVATIVES USEFUL FOR THE TREATMENT OF KINASE - INDUCED DISEASES
Document Type and Number:
WIPO Patent Application WO/2012/003912
Kind Code:
A8
Abstract:
The present invention relates to novel bipyridyl derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.
Inventors:
HOELZEMANN GUENTER (DE)
DORSCH DIETER (DE)
JONCZYK ALFRED (DE)
AMENDT CHRISTIANE (DE)
ZENKE FRANK (DE)
DORSCH DIETER (DE)
JONCZYK ALFRED (DE)
AMENDT CHRISTIANE (DE)
ZENKE FRANK (DE)
Application Number:
PCT/EP2011/002788
Publication Date:
March 08, 2012
Filing Date:
June 07, 2011
Export Citation:
Assignee:
MERCK PATENT GMBH
HOELZEMANN GUENTER (DE)
DORSCH DIETER (DE)
JONCZYK ALFRED (DE)
AMENDT CHRISTIANE (DE)
ZENKE FRANK (DE)
HOELZEMANN GUENTER (DE)
DORSCH DIETER (DE)
JONCZYK ALFRED (DE)
AMENDT CHRISTIANE (DE)
ZENKE FRANK (DE)
International Classes:
C07D213/74; A61K31/444; A61K31/4545; A61K31/4709; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61P25/00; A61P29/00; A61P35/00; C07D401/14; C07D471/04
Attorney, Agent or Firm:
MERCK PATENT GMBH (Darmstadt, Allemagne, DE)
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