Title:
BIS-TRANSITION-METAL-CHELATE-PROBES
Document Type and Number:
WIPO Patent Application WO2003091689
Kind Code:
A3
Abstract:
A probe for labeling a target material is provided including two transition-metal chelates and detectable group. The probe has the general structural formula (I) wherein: (a) Y and Y' are each a transition metal, (b) R<1> and R<1> are each independently CH(COO-), CH(COOH), or absent; (c)R<2> and R<2 >are linkers each having a length of from about 3.0 to about 20 Å; and (d) X is a detectable group. The linkers may be linear or branched, may contain aromatic moeties, and may optionally be further substituted. Methods of use of the probe in detecting and analyzing target materials of interest also are provided.
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Inventors:
EBRIGHT RICHARD H (US)
EBRIGHT YON W (US)
EBRIGHT YON W (US)
Application Number:
PCT/US2002/036180
Publication Date:
December 23, 2004
Filing Date:
November 12, 2002
Export Citation:
Assignee:
RUTGERS THE STATE OF UNIVERSIT (US)
EBRIGHT RICHARD H (US)
EBRIGHT YON W (US)
EBRIGHT RICHARD H (US)
EBRIGHT YON W (US)
International Classes:
C07D209/14; (IPC1-7): G01N33/532; C07D209/14
Domestic Patent References:
| WO2001052744A1 | 2001-07-26 | |||
| WO2001064708A1 | 2001-09-07 | |||
| WO2000009169A1 | 2000-02-24 | |||
| WO2001081365A2 | 2001-11-01 | |||
| WO2000047548A1 | 2000-08-17 | |||
| WO2002059076A1 | 2002-08-01 | |||
| WO2002038546A1 | 2002-05-16 | |||
| WO1993011433A1 | 1993-06-10 |
Foreign References:
| US4761481A | 1988-08-02 |
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