Title:
BIS(ALKYLTHIO)CARBENIUM SALTS
Document Type and Number:
WIPO Patent Application WO2002064583
Kind Code:
A3
Abstract:
The invention relates to bis(alkylthio)carbenium salts of formula (I) wherein R<1>, R<2>, R<3> and Y<-> have the cited designations, and a method for the production of the same. The inventive compounds are advantageously suitable as electrophilic reagents for transferring fluorinated alkyl and acyl radicals to nucleophilic compounds.
Inventors:
KIRSCH PEER (DE)
RUHL ANDREAS (DE)
ROESCHENTHALER GERD-VOLKER (DE)
SEVENARD DIMITRII (DE)
RUHL ANDREAS (DE)
ROESCHENTHALER GERD-VOLKER (DE)
SEVENARD DIMITRII (DE)
Application Number:
PCT/EP2002/001401
Publication Date:
October 03, 2002
Filing Date:
February 11, 2002
Export Citation:
Assignee:
MERCK PATENT GMBH (DE)
KIRSCH PEER (DE)
RUHL ANDREAS (DE)
ROESCHENTHALER GERD-VOLKER (DE)
SEVENARD DIMITRII (DE)
KIRSCH PEER (DE)
RUHL ANDREAS (DE)
ROESCHENTHALER GERD-VOLKER (DE)
SEVENARD DIMITRII (DE)
International Classes:
C07B61/00; C07C17/093; C07C17/35; C07C22/08; C07C41/22; C07C43/12; C07C45/56; C07C49/80; C07C327/36; C07C381/00; C07D339/08; C07D409/04; (IPC1-7): C07D339/08; C07C327/36; C07D409/04
Foreign References:
| DE3700825A1 | 1987-07-30 | |||
| EP0294228A2 | 1988-12-07 |
Other References:
CADAMURO ET AL.: "2-Substituted 1,3-benzoxathiolium ...", SYNTHESIS, vol. 7, 1987, pages 544 - 547, XP002206234
MOCERINO ET AL.: "2-Phenyl-1,3-benzhodithiolium trifluoromethansulfonate...", TETRAHEDRON LETT., vol. 31, no. 21, 1990, pages 3051 - 3054, XP001088235
KUROBOSHI ET AL.: "Synthesis of perfluoroalkyl-substituted arenes...", J.FLUORINE CHEM., vol. 69, no. 2, 1994, pages 127 - 128, XP002206235
WANG J-Q ET AL: "ASYMMETRIC TOTAL SYNTHESIS OF (+)-(3R,4S,5R,7S)- NEOCLAUSENAMIDE", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL SOCIETY. LETCHWORTH, GB, no. 2, 1996, pages 209 - 212, XP000916286, ISSN: 0368-1769
OKUYAMA: "Cyclic dithio-carbenium ion salts...", TETRAHEDRON LETT., vol. 23, no. 26, 1982, pages 2665 - 2666, XP001088236
SIEBER: "Modification of tryptophan...", TETRAHEDRON LETT., vol. 28, no. 15, 1987, pages 1637 - 1640, XP001087882
MOCERINO ET AL.: "2-Phenyl-1,3-benzhodithiolium trifluoromethansulfonate...", TETRAHEDRON LETT., vol. 31, no. 21, 1990, pages 3051 - 3054, XP001088235
KUROBOSHI ET AL.: "Synthesis of perfluoroalkyl-substituted arenes...", J.FLUORINE CHEM., vol. 69, no. 2, 1994, pages 127 - 128, XP002206235
WANG J-Q ET AL: "ASYMMETRIC TOTAL SYNTHESIS OF (+)-(3R,4S,5R,7S)- NEOCLAUSENAMIDE", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL SOCIETY. LETCHWORTH, GB, no. 2, 1996, pages 209 - 212, XP000916286, ISSN: 0368-1769
OKUYAMA: "Cyclic dithio-carbenium ion salts...", TETRAHEDRON LETT., vol. 23, no. 26, 1982, pages 2665 - 2666, XP001088236
SIEBER: "Modification of tryptophan...", TETRAHEDRON LETT., vol. 28, no. 15, 1987, pages 1637 - 1640, XP001087882
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