BLOOD COLLECTION DEVICE FOR STABILIZING CELL -FREE PLASMA DNA

Title:

BLOOD COLLECTION DEVICE FOR STABILIZING CELL -FREE PLASMA DNA

Document Type and Number:

WIPO Patent Application WO/2013/123030

Kind Code:

A3

Abstract:

Methods and devices for stabilizing and preserving circulating cell- free plasma DNA for analysis are disclosed. The methods and devices use diazolidinyl urea or imidazolidinyl urea as a preservative, EDTA as an anticoagulant and glycine as a quenching agent to quench any free formaldehyde from the protective composition.

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Inventors:

RYAN WAYNE L (US)
FERNANDO M ROHAN (US)
DAS KAUSIK (US)

Application Number:

PCT/US2013/025912

Publication Date:

October 31, 2013

Filing Date:

February 13, 2013

Export Citation:

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Assignee:

STRECK INC (US)

International Classes:

C12Q1/68

Foreign References:

US20100184069A1

2010-07-22

Other References:

SCHATZ ET AL.: "PRESERVATION OF CELL-FREE DNA IN STORED BLOOD SAMPLES FOR THE ANALYSIS OF THE (M)SEPT9 COLORECTAL CANCER SCREENING MARKER ENABLES SAMPLE SHIPMENT BY MAIL", May 2011 (2011-05-01), Published as a poster at the conference on international federation of clinical chemistry and laboratory medicine Worldlab and EU, Berlin, Germany, XP002699458, Retrieved from the Internet [retrieved on 20130625]

Attorney, Agent or Firm:

PURSLEY, Kristen L. et al. (P.C.29 W. Lawrence Street, Suite 21, Pontiac MI, US)

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