Title:
BLOOD TESTING METHOD FOR MACROLIDE IMMUNOSUPPRESSANT
Document Type and Number:
WIPO Patent Application WO/2019/131380
Kind Code:
A1
Abstract:
The present invention provides simple and/or high-precision blood testing for a macrolide immunosuppressant. Specifically, the present invention provides a blood testing method for a macrolide immunosuppressant, comprising the following: (a) treating a blood sample that contains a macrolide immunosuppressant, or a metabolite thereof having a macrolide structure, with an acid or alkali; and (b) using an antibody to measure the concentration of the macrolide immunosuppressant or the metabolite in the blood sample.
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Inventors:
TOYONAGA MASAYA (JP)
HOTTA YOSHIYUKI (JP)
HOTTA YOSHIYUKI (JP)
Application Number:
PCT/JP2018/046785
Publication Date:
July 04, 2019
Filing Date:
December 19, 2018
Export Citation:
Assignee:
FUJIREBIO KK (JP)
International Classes:
G01N33/48; G01N33/53
Domestic Patent References:
| WO2010092958A1 | 2010-08-19 | |||
| WO2004011644A1 | 2004-02-05 | |||
| WO2013042426A1 | 2013-03-28 |
Foreign References:
| JP2001514737A | 2001-09-11 | |||
| JP2016540220A | 2016-12-22 | |||
| JP2011506973A | 2011-03-03 | |||
| JP2010515064A | 2010-05-06 | |||
| US20110318754A1 | 2011-12-29 | |||
| JP2008538001A | 2008-10-02 | |||
| JPS5124467B1 | 1976-07-24 | |||
| JPS5134692B1 | 1976-09-28 | |||
| JP5450092B2 | 2014-03-26 | |||
| JP4968611B2 | 2012-07-04 | |||
| JP5174898B2 | 2013-04-03 | |||
| JP5690888B2 | 2015-03-25 | |||
| JPS4940438B1 | 1974-11-01 |
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BIOCHEM. BIOPHYS. RES. COMMUN., vol. 202, no. 1, 15 July 1994 (1994-07-15), pages 437 - 443
DRUG METABOLISM AND DISPOSITION, vol. 21, no. 6, November 1993 (1993-11-01), pages 971 - 977
BR. J. CLIN. PHARMACOL., vol. 55, no. 2, February 2003 (2003-02-01), pages 203 - 211
CLIN. BIOCHEM., vol. 24, no. 1, February 1991 (1991-02-01), pages 71 - 74
CLIN. CHEM., vol. 37, no. 3, 1991, pages 403 - 410
THER. DRUG. MONIT., vol. 37, no. 3, June 2015 (2015-06-01), pages 395 - 399
CLIN. BIOCHEM., vol. 29, no. 4, August 1996 (1996-08-01), pages 309 - 313
THER. DRUG MONIT., vol. 29, no. 6, December 2007 (2007-12-01), pages 743 - 749
NUCLEIC ACIDS RES., vol. 39, no. 3, February 2011 (2011-02-01), pages el4
Attorney, Agent or Firm:
SAKAI INTERNATIONAL PATENT OFFICE (JP)
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