Title:
BONE DELIVERY CONJUGATES AND METHOD OF USING SAME TO TARGET PROTEINS TO BONE
Document Type and Number:
WIPO Patent Application WO2005103263
Kind Code:
B1
Abstract:
A bone delivery conjugate having a structure selected from the group consisting of :A) X-Dn-Y-protein-Z; and B) Z-protein-Y- Dn-X, wherein X is absent or is an amino acid sequence of at least one amino acid; Y is absent or is an amino acid sequence of at least one amino acid; Z is absent or is an amino acid sequence of at least one amino acid; and Dn is a poly aspartate wherein n = 10 to 16. Compositions comprising same and uses thereof.
Inventors:
CRINE PHILIPPE (CA)
BOILEAU GUY (CA)
LEMIRE ISABELLE (CA)
LOISEL THOMAS P (CA)
BOILEAU GUY (CA)
LEMIRE ISABELLE (CA)
LOISEL THOMAS P (CA)
Application Number:
PCT/CA2005/000615
Publication Date:
December 15, 2005
Filing Date:
April 21, 2005
Export Citation:
Assignee:
ENOBIA PHARMA INC (CA)
CRINE PHILIPPE (CA)
BOILEAU GUY (CA)
LEMIRE ISABELLE (CA)
LOISEL THOMAS P (CA)
CRINE PHILIPPE (CA)
BOILEAU GUY (CA)
LEMIRE ISABELLE (CA)
LOISEL THOMAS P (CA)
International Classes:
A61K38/46; A61K38/48; A61K47/48; A61K47/64; A61P19/08; C12N9/14; C12N9/50; C12N9/64; C12N15/55; C12N15/57; G01N33/68; (IPC1-7): C12N15/57; A61K38/46; A61K38/48; A61K47/48; C12N15/55; C12N9/50; C12N9/14; A61P19/08; G01N33/68
Download PDF:
Previous Patent: A NOVEL DIOL DEHYDRATASE GENE CLUSTER IN LISTERIA GENUS
Next Patent: PROCESS FOR THE PREPARATION OF RECOMBINANT AMEDIPLASE
Next Patent: PROCESS FOR THE PREPARATION OF RECOMBINANT AMEDIPLASE