Title:
BORON AND PHOSPHORUS-BASED BIOACTIVE GLASS AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/148554
Kind Code:
A1
Abstract:
Disclosed are a boron and phosphorus-based bioactive glass and a preparation method thereof. The method comprises the steps of preparing a boron-based glass by melt-quenching method, wherein the raw materials includes B 2O 3, MgO, CaO, Na 2O, K 2O和SrO and SrO in a mass ratio of (45-60):(2-10):(15-25):(3-10):(10-15):(1-8); and then impregnating in a solution containing phosphorus ions to yield a double-layer bioactive glass with a porous phosphate shell and a borate core. The degradation rate of the borate glass structure in an organism can be controlled, and the biocompatibility of the biological material can be improved by the porous shell; and therefore, the repairing speed of an injured body surface tissue is significantly increased.
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Inventors:
LIU HONGLIN (CN)
CHEN RUIGUO (CN)
HUANG PEIYAN (CN)
LI QIAN (CN)
WANG JUNFENG (CN)
ZHANG TENG (CN)
FU YUHONG (CN)
CHEN RUIGUO (CN)
HUANG PEIYAN (CN)
LI QIAN (CN)
WANG JUNFENG (CN)
ZHANG TENG (CN)
FU YUHONG (CN)
Application Number:
PCT/CN2018/077009
Publication Date:
August 08, 2019
Filing Date:
February 23, 2018
Export Citation:
Assignee:
FUZHOU RUIKE BULANG MEDICAL TECH CO LTD (CN)
International Classes:
C03C3/14
Domestic Patent References:
| WO2014159240A1 | 2014-10-02 |
Foreign References:
| US6709744B1 | 2004-03-23 | |||
| CN102430149A | 2012-05-02 | |||
| CN106630646A | 2017-05-10 | |||
| CN107617121A | 2018-01-23 |
Other References:
HAN, XUE ET AL.: "Reaction of Sodium Calcium Borate Glasses to Form Hydroxyapatite", J MATER SCI: MATER MED, 8 May 2007 (2007-05-08), pages 1838, XP019529234
Attorney, Agent or Firm:
FUZHOU YUANCHUANG PATENT AND TRADEMARK AGENT LTD. (CN)
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