Title:
BRAIN HEALTH FOOD OR BRAIN HEALTH BEVERAGE, AND METHOD FOR ADMINISTERING SAME
Document Type and Number:
WIPO Patent Application WO/2017/150475
Kind Code:
A1
Abstract:
[Problem] To develop a brain health food/brain health beverage for preventing/alleviating brain atrophy due to alcohol intake. [Solution] A brain health food or brain health beverage containing, as active ingredients, folic acid, vitamin B6, and vitamin B12, for preventing a decrease in the brain capacity of regular drinkers who are not suffering from dementia, i.e., healthy people, the brain health food or brain health beverage being characterized in containing, as active ingredients, 0.4-0.8 mg of folic acid, 10-20 mg of vitamin B6, and 0.25-0.5 mg of vitamin B12.
Inventors:
PARK KAECHANG (JP)
Application Number:
PCT/JP2017/007573
Publication Date:
September 08, 2017
Filing Date:
February 27, 2017
Export Citation:
Assignee:
KOCHI PREFECTURAL PUBLIC UNIV CORP (JP)
International Classes:
A23L33/15; A23L2/52; A61K31/4415; A61K31/519; A61K31/714; A61P25/28
Foreign References:
| JP2009173640A | 2009-08-06 | |||
| JP2004168699A | 2004-06-17 |
Other References:
SMITH A. D. ET AL.: "Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial", PLOS ONE, vol. 5, no. 9, September 2010 (2010-09-01), pages 1 - 10, XP055218522
DOUAUD, G. ET AL.: "Preventing Alzheimer's disease-related gray matter atrophy by B- vitamin treatment", PROC. NATL. ACAD. SCI. USA, vol. 110, no. 23, June 2013 (2013-06-01), pages 9523 - 9528, XP055462331
JAGER C. A. ET AL.: "Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial", INT. J. GERIATR. PSYCHIATRY, vol. 27, 2012, pages 592 - 600, XP009186504
"Areare.Soresore' to Namae ya Kaiwa ga Smooth ni Denai Anata ya Gokazoku, Goryoshin ni ... 'Memorin' Shinhatsubai!!", INNOVATIONSS-I PRESS RELEASE, April 2014 (2014-04-01), pages 1 - 5, XP009516111, Retrieved from the Internet [retrieved on 20170517]
PAUL C. A. ET AL.: "Association of Alcohol Consumption With Brain Volume in the Framingham Study", ARCH. NEUROL., vol. 65, no. 10, 1 October 2008 (2008-10-01), pages 1363 - 1367, XP055576069, DOI: 10.1001/archneur.65.10.1363
ANSTEY K. J. ET AL.: "Weekly Alcohol Consumption, Brain Atrophy, and White Matter Hyperintensities in a Community-Based Sample Aged 60 to 64 Years", PSYCHOSOM. MED., vol. 68, no. 5, 1 September 2006 (2006-09-01), pages 778 - 785, XP055576063, DOI: 10.1097/01.psy.0000237779.56500.af
TAKAO HASHIMOTO ET AL: "Homocysteine Metabolism", YAKUGAKU ZASSHI, vol. 127, no. 10, 1 October 2007 (2007-10-01), pages 1579 - 1592, XP055576076, DOI: 10.1248/yakushi.127.1579
ARCHIVES OF NEUROLOGY, vol. 65, no. 10, 2008, pages 1363 - 1367
STROKE, vol. 32, 2001, pages 1116 - 1119
PLOS ONE, vol. 5, no. 9, 2010, pages 1 - 10
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (PNAS, vol. 110, no. 23, 2013, pages 9523 - 9528
INT.J.GERIATR.PSYCHIATRY, vol. 27, 2012, pages 592 - 600
See also references of EP 3424350A4
DOUAUD, G. ET AL.: "Preventing Alzheimer's disease-related gray matter atrophy by B- vitamin treatment", PROC. NATL. ACAD. SCI. USA, vol. 110, no. 23, June 2013 (2013-06-01), pages 9523 - 9528, XP055462331
JAGER C. A. ET AL.: "Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial", INT. J. GERIATR. PSYCHIATRY, vol. 27, 2012, pages 592 - 600, XP009186504
"Areare.Soresore' to Namae ya Kaiwa ga Smooth ni Denai Anata ya Gokazoku, Goryoshin ni ... 'Memorin' Shinhatsubai!!", INNOVATIONSS-I PRESS RELEASE, April 2014 (2014-04-01), pages 1 - 5, XP009516111, Retrieved from the Internet
PAUL C. A. ET AL.: "Association of Alcohol Consumption With Brain Volume in the Framingham Study", ARCH. NEUROL., vol. 65, no. 10, 1 October 2008 (2008-10-01), pages 1363 - 1367, XP055576069, DOI: 10.1001/archneur.65.10.1363
ANSTEY K. J. ET AL.: "Weekly Alcohol Consumption, Brain Atrophy, and White Matter Hyperintensities in a Community-Based Sample Aged 60 to 64 Years", PSYCHOSOM. MED., vol. 68, no. 5, 1 September 2006 (2006-09-01), pages 778 - 785, XP055576063, DOI: 10.1097/01.psy.0000237779.56500.af
TAKAO HASHIMOTO ET AL: "Homocysteine Metabolism", YAKUGAKU ZASSHI, vol. 127, no. 10, 1 October 2007 (2007-10-01), pages 1579 - 1592, XP055576076, DOI: 10.1248/yakushi.127.1579
ARCHIVES OF NEUROLOGY, vol. 65, no. 10, 2008, pages 1363 - 1367
STROKE, vol. 32, 2001, pages 1116 - 1119
PLOS ONE, vol. 5, no. 9, 2010, pages 1 - 10
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (PNAS, vol. 110, no. 23, 2013, pages 9523 - 9528
INT.J.GERIATR.PSYCHIATRY, vol. 27, 2012, pages 592 - 600
See also references of EP 3424350A4
Attorney, Agent or Firm:
KIYOHARA Yoshihiro (JP)
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