BRYOSTATINS, BRYOPYRANS AND POLYKETIDES: COMPOSITIONS AND METHODS

WIPO Patent Application WO2003099219

A3

The present invention provides nucleic acid molecules that encode polypeptides that catalyze the synthesis of bioactive compounds, such as polyketides including bryopyran rings, such as bryostatins. Also provided is a composition including at least one nucleic acid molecule that encodes at least one polypeptide that catalyzes at least one step in the synthesis of at least one polyketide such as a bryopyran ring, wherein said at least one nucleic acid molecule is derived from at least one marine organism.

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HAYGOOD MARGO (US)
HILDEBRAND MARK (US)
ANDERSON CHRISTINE (US)
WAGGONER LAURA E (US)
SHERMAN DAVID H (US)
LIU HAIBIN (US)

PCT/US2003/016299

March 03, 2005

May 20, 2003

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UNIV CALIFORNIA (US)
HAYGOOD MARGO (US)
HILDEBRAND MARK (US)
ANDERSON CHRISTINE (US)
WAGGONER LAURA E (US)
SHERMAN DAVID H (US)
LIU HAIBIN (US)

A61K48/00; C07H21/00; C12N15/52; C12P17/18; C12Q1/68; A61K; (IPC1-7): A61K48/00; C07H21/00; C12Q1/68

WO2001011024A2

2001-02-15

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