BULK FREEZING OF BIOPHARMACEUTICALS - PRAXAIR TECHNOLOGY INC

Title:

BULK FREEZING OF BIOPHARMACEUTICALS

Document Type and Number:

WIPO Patent Application WO/2012/135216

Kind Code:

A3

Abstract:

A system and method for bulk freezing is provided. In one embodiment, the system and method for bulk freezing includes a bulk freezing container adapted to hold at least one and preferably a plurality of bags holding a biopharmaceutical liquid. The bulk freezing container includes at least a first and second shelf having corrugations wherein the second shelf is vertically arranged above the first shelf with the bags disposed between the shelves. The bags and the corrugations of the first and second shelves define a plurality of substantially parallel flow channels through which a cryogenic cold fluid or a warming fluid is passed to freeze and/or thaw the biopharmaceutical fluid. In another embodiment, the bulk freezing system and method includes a bulk freezing container with a plurality of adjacent elongated chambers adapted for holding the biopharmaceutical fluid.

Inventors:

ZHOU YING (US)
CHENG ALAN (US)
GRINTER NIGEL (US)
FOWLER ZACHARY (US)
SEVER ROBERT (US)
BURSAC RANKO (US)

Application Number:

PCT/US2012/030738

Publication Date:

May 01, 2014

Filing Date:

March 27, 2012

Export Citation:

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Assignee:

PRAXAIR TECHNOLOGY INC (US)
ZHOU YING (US)
CHENG ALAN (US)
GRINTER NIGEL (US)
FOWLER ZACHARY (US)
SEVER ROBERT (US)
BURSAC RANKO (US)

International Classes:

F25D31/00

Foreign References:

US20090133411A1	2009-05-28
US20070186437A1	2007-08-16
US3365806A	1968-01-30
US20090044546A1	2009-02-19

Other References: