Title:
C. NOVYI FOR THE TREATMENT OF SOLID TUMORS IN NON-HUMAN ANIMALS
Document Type and Number:
WIPO Patent Application WO/2014/160967
Kind Code:
A8
Abstract:
The present invention provides, inter alia, methods for treating or ameliorating an effect of a solid tumor present in a non-human animal. These methods include administering intratumorally to the non-human animal a unit dose of C. novyi, preferably C. novyi NT, colony forming units (CFUs), which contains about 1 x 106-1 x 1010 CFUs suspended in a pharmaceutically acceptable carrier or solution. Methods for debulking a solid tumor present in a non-human animal, a method for microscopically precise excision of tumor cells in a non-human animal, methods for treating or ameliorating an effect of a solid tumor that has metastasized to one or more sites in a non-human animal, methods for ablating a solid tumor present in a non-human animal, unit doses of C. novyi, preferably C. novyi NT, CFUs, and kits for treating or ameliorating an effect of a solid tumor present in a non-human animal are also provided.
Inventors:
SAHA SAURABH (US)
Application Number:
PCT/US2014/032224
Publication Date:
April 30, 2015
Filing Date:
March 28, 2014
Export Citation:
Assignee:
BIOMED VALLEY DISCOVERIES INC (US)
International Classes:
A01N63/00; A61K35/66; C12N1/20
Attorney, Agent or Firm:
HOOPER, Kevin C. (1290 Avenue of the AmericasNew York, New York, US)
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